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ProteomicsThe mass spectrometric intact transition epitope mapping method supports protein engineering of foldon trimer variants
The wild-type foldon (foldon 0) is the C-terminal trimerization domain of the bacteriophage T4 Fibritin foldon (T4Ff). T4Ff’s amino acid sequence is GYIPEAPRDGQAYVRKDGEWVLLSTFL (27 amino acid residues; single letter code). Foldons 0, 1-6 were synthesized by solid phase peptide synthesis and in foldo...
ORGANISM(S): Enterobacteria phage T4 (Bacteriophage T4) 
2025-11-28 | PXD064233 | Pride
ProteomicsIntact Transition Epitope Mapping - Forces of Interactions between Variants of Equivalent macromolecules (ITEM-FIVE)
Foldon (F) is a specific partial sequence from the C-terminal domain of T4 fibritin, which is found at the neck of the T4 bacteriophage. The amino acid sequence (27 residues) in single letter code is GYIPEAPRDGQAYVRKDGEWVLLSTFL. In neutral solution (pH 6.9) it forms a homo-trimer (F-F-F). Biotinylat...
ORGANISM(S): Enterobacteria phage T4 (Bacteriophage T4) 
2024-04-29 | PXD044721 | Pride
Item-two Hetero-trimer Offline esi-ms Foldon Complex dissociation Homo-trimer Gas phase 
UnknownThe foldon substructure of staphylococcal nuclease.
Not available
S-EPMC2268249 | biostudies-literature
UnknownFoldon-guided self-assembly of ultra-stable protein fibers.
Not available
S-EPMC2525528 | biostudies-literature
UnknownReassessing the exon-foldon correspondence using frustration analysis.
Not available
S-EPMC11252736 | biostudies-literature
UnknownOligomerization triggered by foldon: a simple method to enhance the catalytic efficiency of lichenase and xylanase.
Not available
S-EPMC5496177 | biostudies-literature
UnknownCytochrome c folds through foldon-dependent native-like intermediates in an ordered pathway.
Not available
S-EPMC4833275 | biostudies-literature
UnknownA foldon-free prefusion F trimer vaccine for respiratory syncytial virus to reduce off-target immune responses.
Not available
S-EPMC11602707 | biostudies-literature
UnknownFoldon unfolding mediates the interconversion between M(pro)-C monomer and 3D domain-swapped dimer.
Not available
S-EPMC3443179 | biostudies-literature
UnknownRational Design of a Foldon-Derived Heterotrimer Guided by Quantitative Native Mass Spectrometry.
Not available
S-EPMC12352491 | biostudies-literature
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