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TranscriptomicsRNA-seq profiling of theca and granulosa tissue of dominant follicle at 3 stages of follicular development in cows and heifers.
Cellular mechanisms that contribute to low estradiol concentrations produced by the preovulatory ovarian follicle in cattle with a compromised metabolic status (such as lactatino) are largely unknown. To gain insight into the main metabolic mechanisms affecting preovulatory follicle function RNAseq ...
ORGANISM(S): Bos taurus 
2012-06-15 | E-GEOD-34317 | biostudies-arrayexpress
TranscriptomicsGene Bionetwork Analysis of Ovarian Primordial Follicle Development
Ovarian primordial follicles are critical for female reproduction and comprise a finite pool of gametes arrested in development. A systems biology approach was used to identify regulatory gene networks essential for primordial follicle development. Transcriptional responses to eight different growth...
ORGANISM(S): Rattus norvegicus 
2010-06-13 | E-GEOD-20324 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat ovary during primordial follicle assembly and development.
The assembly of the developmentally arrested primordial follicle and subsequent transition to the primary follicle are poorly understood processes critical to ovarian biology. Abnormal primordial follicle development can lead to pathologies such as premature ovarian failure. The current study used a...
ORGANISM(S): Rattus norvegicus 
2008-06-16 | E-GEOD-9300 | biostudies-arrayexpress
TranscriptomicsGene expression in bovine ovarian follicle theca interna
Thecal tissue forms a layer around the follicle just prior to antral stage and grows with the follicle (containing an oocyte) as it matures. The innermost component (theca interna) supplies hormones and other factors necessary to the growth and development of the granulosa and oocyte. Most follicles...
ORGANISM(S): Bos taurus 
2014-05-20 | E-GEOD-49505 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Bos taurus granulosa and theca cells during ovarian antral follicle development.
Coordinated interactions between ovarian granulosa and theca cells are required for female endocrine function and fertility. To elucidate these interactions the regulation of the granulosa and theca cell transcriptomes during bovine antral follicle development were investigated. Granulosa cells and ...
ORGANISM(S): Bos taurus 
2008-11-04 | E-GEOD-11495 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat folliculogenesis reveals glial derived neurotrophic factor promotes ovarian primordial follicle development
Female fertility is determined in part by the size and development of the primordial follicle pool. The current study investigates the role of glial cell-line derived neurotrophic factor (GDNF) in the regulation of primordial follicle development in the ovary. Ovaries from four-day old female rat pu...
ORGANISM(S): Rattus norvegicus 
2008-06-11 | E-GEOD-11133 | biostudies-arrayexpress
TranscriptomicsNeurotrophin NT3 promotes ovarian primordial to primary follicle transition
Neurotrophins are growth factors that are known to have a role in promoting cell survival and differentiation. The focus of the current study is to examine the role of neurotrophins in regulating ovarian primordial follicle development. Ovaries from 4-day old rats were placed into organ culture and ...
ORGANISM(S): Rattus norvegicus 
2010-02-21 | E-GEOD-20358 | biostudies-arrayexpress
TranscriptomicsGene expression in bovine ovarian follicle granulosa
Granulosa cells mature and die as ovarian follicles enlarge and die (undergo atresia) under the influence of hormones and intrafollicular factors. Later in follicular development, a fluid-filled antrum is formed, a process which is accompanied by a high rate of atresia. These small antral follicles ...
ORGANISM(S): Bos taurus 
2014-05-20 | E-GEOD-39589 | biostudies-arrayexpress
TranscriptomicsCGH Follicle OregonR-Orr-Weaver
modENCODE_submission_724 This submission comes from a modENCODE project of David MacAlpine. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: Most terminally differentiated Drosophila tissues are either polyploid or polytene. Unlike normal chromosomes, where the...
ORGANISM(S): Drosophila melanogaster 
2010-05-15 | E-GEOD-17291 | biostudies-arrayexpress
TranscriptomicsCGH Follicle OregonR-mod
modENCODE_submission_723 This submission comes from a modENCODE project of David MacAlpine. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: Most terminally differentiated Drosophila tissues are either polyploid or polytene. Unlike normal chromosomes, where the...
ORGANISM(S): Drosophila melanogaster 
2010-05-15 | E-GEOD-17290 | biostudies-arrayexpress
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