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MetabolomicsA Randomized Controlled Trial of Shengji Ointment Combined with Bromelain in Promoting Healing of Tendon-Exposed Diabetic Foot Wounds: Metabolomics Profiling Analysis

Background: Diabetic foot tendon exposures are prone to infection, necrosis, and prolonged treatment cycles, not only hindering wound healing but potentially leading to amputation and life-threatening complications. Shengji ointment combined with bromelain has demonstrated preliminary efficacy i...

2025-07-14 | MTBLS12713 | MetaboLights
MetabolomicsArginine depletion-induced autophagy and metabolic dysregulation are involved in the disease severity of hand, foot, and mouth disease
Amino acid metabolism provides significant insight into the development and prevention of many viral diseases. Therefore, the present study aimed to compare the amino acid profiles of hand, foot, and mouth disease (HFMD) patients with those of healthy individuals and to further reveal the molecular ...
2024-10-25 | MTBLS11341 | MetaboLights
ProteomicsInvestigating byssogenesis with proteomic analysis of byssus, foot and mantle in Mytilus mussels by LC-MS/MS
Mussels synthesize an interesting class of biological materials with unique properties to adhere onto virtually any solid surface. Inter- and cross-species analyses have revealed that mussel byssus fabrication is influenced by environmental factors. In this study, proteins expressed specifically bys...
ORGANISM(S): Mytilus edulis (Blue mussel) Mytilus californianus 
2020-09-17 | PXD021023 | Pride
Mussel Byssus Bottom-up proteomics Foot Lc-ms/ms 
TranscriptomicsMicroRNA of exosome in Hand, foot and mouth disease serum samples
The some biomarkers can be found by pairwise comparison. They can distinguish between extremely severe Hand,foot and mouth disease and mild Hand,foot and mouth disease,moreover,they can applied to diagnose extremely severe Hand,foot and mouth disease mild Hand,foot and mouth disease vs.control; extr...
ORGANISM(S): Homo sapiens 
2013-11-27 | E-GEOD-52780 | biostudies-arrayexpress
GenomicsFoot-and-mouth disease virus strain:Serotype Asia1
Foot-and-mouth disease virus strain:Serotype Asia1 Raw sequence reads
PRJNA415691 | ENA
TranscriptomicsComparative genomic, microRNA, and tissue analyses reveal subtle differences between non-diabetic and diabetic foot skin [nanoString nCounter miR expression assay]
Diabetes Mellitus (DM) is a chronic, severe disease rapidly increasing in incidence and prevalence and is associated with numerous complications. Patients with DM are at high risk of developing diabetic foot ulcers (DFU) that often lead to lower limb amputations, long term disability, and a shortene...
ORGANISM(S): Homo sapiens 
2015-05-01 | E-GEOD-68185 | biostudies-arrayexpress
ProteomicsSRGAP1 controls small Rho GTPases to regulate podocyte foot process maintenance
Podocyte foot process effacement and proteinuria is a common and uniform consequence of glomerular injury. Previously it has been shown that small Rho GTPases (e.g. RAC1) are drivers of podocyte foot process effacement in glomerular diseases such as focal segmental glomerulosclerosis (FSGS). However...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-07-30 | MSV000085853 | MassIVE
GenomicsFoot-and-mouth disease virus
Foot-and-mouth disease virus sequencing
PRJNA1196655 | ENA
MetabolomicsFree fatty acid generation via Rhein-induced LDL-C endocytosis accelerates biofilm infected diabetic wound healing

Diabetic foot infection (DFI) significantly increases risks of hospitalization and amputation, with biofilm infections caused by methicillin-resistant Staphylococcus aureus (MRSA) and carbapenem-resistant Enterobacteriaceae (CRE) being key drivers of treatment failure. Here, we ana...

2026-01-06 | MTBLS13603 | MetaboLights
GenomicsFoot-and-mouth disease virus
Foot-and-mouth disease virus cattle coinfection experiment 2022
PRJNA1026883 | ENA
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