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TranscriptomicsGlucocorticoid Resistance Gene Profiling in T-ALL Cell Lines
Baseline glucocorticoid resistance profiles were measured in a panel of 15 paediatric T-Cell acute lymphoblastic leukaemia cell lines and correlated with Affymetrix Gene expression to identify genes and pathways associated with drug resistance in T-ALL. The cell lines' resistance to Methylprednisolo...
ORGANISM(S): Homo sapiens 
2012-07-09 | E-MTAB-1208 | biostudies-arrayexpress
TranscriptomicsGene based outcome prediction in pediatric T-cell acute lymphoblastic leukemia
RNA was extracted from the diagnostic bone marrow specimens of 50 T-cell acute lymphoblastic leukemia pediatric patients and analysed by Affymetrix microarray to model gene classifiers predictive of clinical outcome
ORGANISM(S): Homo sapiens 
2012-07-06 | E-MTAB-1205 | biostudies-arrayexpress
TranscriptomicsMurine DN T-reg cells impart prolonged cardiac allograft survival
Recent studies have demonstrated that both mouse and human alpha beta TCR(+)CD3(+)NK1.1(-)CD4(-)CD8- double-negative regulatory T (DN Treg) cells can suppress Ag-specific immune responses mediated by CD8+ and CD4+ T cells. To identify molecules involved in DN Treg cell function, we generated a panel...
ORGANISM(S): Mus musculus 
2005-07-29 | E-GEOD-3024 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse double-negative regulatory T Cells
Lee et al. (2005)Expression Profiling of Murine Double-Negative Regulatory T Cells Suggest Mechanisms for Prolonged Cardiac Allograft Survival. The Journal of Immunology, 2005, 174: 4535 4544. Type 2 experiment where functional DN T-reg cells (CN4 or TN12) were cy-3 labeled and co-hybridized with n...
ORGANISM(S): Mus musculus 
2005-07-21 | E-SMDB-3283 | biostudies-arrayexpress
Unknownβ-Catenin in Dendritic Cells Negatively Regulates CD8 T Cell Immune Responses through the Immune Checkpoint Molecule Tim-3.
Not available
S-EPMC11125945 | biostudies-literature
UnknownGSK-3β in Dendritic Cells Exerts Opposite Functions in Regulating Cross-Priming and Memory CD8 T Cell Responses Independent of β-Catenin.
Not available
S-EPMC11436163 | biostudies-literature
UnknownInnovation in BCMA CAR-T therapy: Building beyond the Model T.
Not available
S-EPMC9729952 | biostudies-literature
TranscriptomicsDistinctive genotypes in infants with T-cell acute lymphoblastic leukaemia
Infant T-cell Acute Lymphoblastic Leukaemia (iT-ALL) is a very rare and poorly defined entity with a poor prognosis. We assembled a unique series of thirteen cases of infants with T-ALL which allowed us to identify genotypic abnormalities and to investigate prenatal origins. Matched samples (diagn...
ORGANISM(S): Homo sapiens 
2015-07-30 | E-GEOD-67271 | biostudies-arrayexpress
UnknownEpigenetic Reprogramming in Naive CD4+ T Cells Favoring T Cell Activation and Non-Th1 Effector T Cell Immune Response as an Early Event in Lupus Flares.
Not available
S-EPMC5001909 | biostudies-literature
UnknownMemory T cell-mediated rejection is mitigated by FcγRIIB expression on CD8+ T cells.
Not available
S-EPMC7395896 | biostudies-literature
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