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TranscriptomicsSphingosine-1-phosphate induces pro-remodelling response in airway smooth muscle cells
Background: Increased proliferation of airway smooth muscle (ASM) cells leading to hyperplasia and increased ASM mass is one of the most characteristic features of airway remodelling in asthma. A bioactive lipid, sphingosine-1-phosphate (S1P), has been suggested to affect airway remodelling by stimu...
ORGANISM(S): Homo sapiens 
2015-06-18 | E-GEOD-58657 | biostudies-arrayexpress
TranscriptomicsHybridPoplar_H11-11_Leaves_MalacosomaDisstria_Herbivory
From a set of 15 standard, normalized or full-length cDNA libraries, we generated 139 007 3'- or 5'-end sequenced ESTs, representing more than one-third of the c. 385 000 publicly available Populus ESTs. Clustering and assembly of 107 519 3'-end ESTs resulted in 14 451 contigs and 20 560 singletons,...
ORGANISM(S): Populus trichocarpa x Populus deltoides 
2008-04-22 | E-GEOD-9522 | biostudies-arrayexpress
Unknown12-hr shifts in nursing: Do they remove unproductive time and information loss or do they reduce education and discussion opportunities for nurses? A cross-sectional study in 12 European countries.
Not available
S-EPMC6916398 | biostudies-literature
UnknownAssociation of obesity with DNA mismatch repair status and clinical outcome in patients with stage II or III colon carcinoma participating in NCCTG and NSABP adjuvant chemotherapy trials.
Not available
S-EPMC3269966 | biostudies-literature
TranscriptomicsLPS and IFNg stimulated mouse airways
Transcription profiling by array was performed on airway wall samples from PBS, LPS, IFN-gamma and LPS+IFN-gamma treated BALB/c mice 12 hr post treatments.
ORGANISM(S): Mus musculus 
2015-10-13 | E-MTAB-1893 | biostudies-arrayexpress
TranscriptomicsExpression data from normal adrenal gland and aldosterone-producing adenoma
The source of aldosterone in 30 to 40 % of patients with primary hyperaldosteronism (PA) is unilateral aldosterone-producing adenoma (APA). The mechanisms causing elevated aldosterone production in APA are unknown. Herein, we examined expression of G-protein coupled receptors (GPCR) in APA and demon...
ORGANISM(S): Homo sapiens 
2007-07-18 | E-GEOD-8514 | biostudies-arrayexpress
TranscriptomicsMicroarray Analysis of Acid-Stress Induced Changes in EHEC O157:H7
While significant advances have been made in EHEC pathogenesis, we still do not fully understand the impact of environmental stress on EHEC virulence. During the course of infection, EHEC must evade or overcome several biological barriers, the first of which is the gastric acidity encountered during...
ORGANISM(S): Escherichia coli 
2010-05-16 | E-GEOD-14069 | biostudies-arrayexpress
UnknownPharmacokinetic and pharmacodynamic properties of calaspargase pegol Escherichia coli L-asparaginase in the treatment of patients with acute lymphoblastic leukemia: results from Children's Oncology Group Study AALL07P4.
Not available
S-EPMC4239306 | biostudies-literature
TranscriptomicsGeneration of Induced Pluripotent Stem Cells using Recombinant Proteins
Groundbreaking work demonstrated that ectopic expression of four transcription factors, Oct4, Klf4, Sox2, and c-Myc, could reprogram murine somatic cells to induced pluripotent stem cells (iPSCs) (Takahashi and Yamanaka, 2006), and human iPSCs were subsequently generated using similar genetic manipu...
ORGANISM(S): Mus musculus 
2010-04-09 | E-GEOD-16062 | biostudies-arrayexpress
TranscriptomicsmiRNA profile of rat vascular smooth muscle cell stimulated by 2.6 mM high-phosphate
We compared time-series miRNA expression profile in high-phosphateM-bM-^@M-^Sstimulated rat vascular smooth muscle cells at 0, 3, and 12 hr respectively. Total RNA of rat VSMCs stimulated with 2.6 mM inorganic phosphate for 0, 3 or 12 hr was harvested by the Trizol method (Invitrogen) or use of the ...
ORGANISM(S): Rattus norvegicus 
2012-07-27 | E-GEOD-39700 | biostudies-arrayexpress
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