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ProteomicsLayers of regulation on cell-cycle gene expression in the budding yeast Saccharomyces cerevisiae
In the budding yeast Saccharomyces cerevisiae, transcription factors (TFs) regulate the periodic expression of many genes during the cell cycle, including gene products required for progression through cell-cycle events. Experimental evidence coupled with quantitative models suggest that a network o...
ORGANISM(S): Saccharomyces Cerevisiae 
PXD010937 | panorama
TranscriptomicsStreptococcus gordonii gene response to the binding of human salivary amylase.
Streptococcus gordonii, an important primary colonizer of dental plaque biofilm, specifically binds to salivary amylase via the surface-associated amylase-binding protein A (AbpA). We hypothesized that amylase binding to S. gordonii modulates expression of chromosomal genes, which could influence ba...
ORGANISM(S): Streptococcus gordonii str. Challis 
2011-09-02 | E-GEOD-31830 | biostudies-arrayexpress
GenomicsEGAS00001000262-sc-20160408 - samples
To characterize the subclonal genomic architecture of non-androgen-deprived metastatic prostate cancer, we performed whole-genome sequencing (WGS) of pelvic lymph node metastases and matching noncancerous blood from 10 patients to an average sequencing depth of 55x. The patients are part of PELICAN ...
EGAD00001002002 | EGA
UnknownInhibition of β-catenin–TCF1 interaction delays differentiation of mouse embryonic stem cells
Not available
S-JCBD-201503017 | bioimages
GenomicsEGAS00001000262-sc-20140722 - samples
To characterize the subclonal genomic architecture of androgen-deprived metastatic prostate cancer, we performed whole-genome sequencing (WGS) of 51 tumours from 10 patients to an average sequencing depth of 55x, including multiple metastases from different anatomic sites in each patient and, in fiv...
EGAD00001000891 | EGA
GenomicsCRUK-ICGC Prostate Cancer Group Study
Prostate cancer somatic genomic sequencing data generated from 2011 onwards under auspices of the International Cancer Genome Consortium Prostate Cancer UK consortium (CRUK-ICGC Prostate Group), co-led by Colin Cooper and Ros Eeles, with other Principal Investigators (Brewer, Neal, Bova, McDermott, ...
EGAS00001000262 | EGA
TranscriptomicsHigh-throughput RT-PCR analysis of Colon Adenocarcinoma Stem Cell Lines
Human early stage colon adenocarcinoma stem cell line was FACS-sorted for CCR9- and CCR9+ cell groups and differential expression was identified via Wafergen SmartChip RT-PCR gene expression profiling. CCR9- and CCR+ cells were FACS-sorted. 24 hours afterwards, cells were treated with 100ng/ml human...
ORGANISM(S): Homo sapiens 
2012-07-01 | E-GEOD-32290 | biostudies-arrayexpress
TranscriptomicsHybrid_Poplar_H11-11_Leaves_Local_Stress_Response_DataSet3
We investigated the transcriptional response of hybrid poplar (Populus trichocarpa x deltoides) leaves to a variety of stress treatments (insect feeding by Malacosoma disstria larvae, mechanical wounding, wounding plus the application of insect oral secretions, and methyl jasmonate spray) over a 24 ...
ORGANISM(S): Populus trichocarpa x Populus deltoides 
2010-09-09 | E-GEOD-14081 | biostudies-arrayexpress
TranscriptomicsHybridPoplar_H11-11_Leaves_MalacosomaDisstria_Herbivory
From a set of 15 standard, normalized or full-length cDNA libraries, we generated 139 007 3'- or 5'-end sequenced ESTs, representing more than one-third of the c. 385 000 publicly available Populus ESTs. Clustering and assembly of 107 519 3'-end ESTs resulted in 14 451 contigs and 20 560 singletons,...
ORGANISM(S): Populus trichocarpa x Populus deltoides 
2008-04-22 | E-GEOD-9522 | biostudies-arrayexpress
TranscriptomicsGlobal monitoring of autumn gene expression within and among populations of Sitka spruce
Cold acclimation in conifers is a complex process, the timing and extent of which reflects local adaptation and varies widely along latitudinal gradients for many temperate and boreal tree species. In spite of their ecological and economic importance, little is known about the global changes in gene...
ORGANISM(S): Picea sitchensis 
2008-05-31 | E-GEOD-8370 | biostudies-arrayexpress
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