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TranscriptomicsCrebA is a major and direct regulator of secretory pathway gene expression
Abstract: Secretion occurs in all cells, with relatively low levels in most cells and extremely high levels in specialized secretory cells, such as those of the pancreas, salivary and mammary glands. Here, we report that the CrebA/Creb3-like family of bZip transcription factors functions to upregul...
ORGANISM(S): Drosophila melanogaster 
2010-10-18 | E-GEOD-23346 | biostudies-arrayexpress
TranscriptomicsFkh1 and Fkh2 Bind Multiple Chromosomal Elements in the S. cerevisiae Genome with Distinct Specificities and Cell Cycle Dynamics
Forkhead box (FOX) transcription factors regulate a wide variety of cellular functions in higher eukaryotes, including cell cycle control and developmental regulation. In Saccharomyces cerevisiae, Forkhead proteins Fkh1 and Fkh2 perform analogous functions, regulating genes involved in cell cycle co...
ORGANISM(S): Saccharomyces cerevisiae 
2014-02-05 | E-GEOD-52467 | biostudies-arrayexpress
TranscriptomicsThe CrebA/Creb3-like transcription factors are major and direct regulators of secretory capacity
Abstract: Secretion occurs in all cells, with relatively low levels in most cells and extremely high levels in specialized secretory cells, such as those of the pancreas, salivary and mammary glands. Here, we report that the CrebA/Creb3-like family of bZip transcription factors functions to upregul...
ORGANISM(S): Homo sapiens 
2010-10-18 | E-GEOD-23349 | biostudies-arrayexpress
TranscriptomicsComparative genomics of Staphylococcus aureus and the application of a “pan-genome” for assigning RNA-Seq transcript reads from divergent strains and in vivo human nasal samples
in vitro comparison between two MRSA grown in rich (BHI) and poor media (SNM), compared with the nasal metatranscriptome reads of S. aureus. Global expression profile of two MRSA strains of S.aureus harvested in two different growth phases and compared with a metatranscriptome nose sample of a S. au...
ORGANISM(S): Staphylococcus aureus 
2015-01-05 | E-GEOD-56294 | biostudies-arrayexpress
TranscriptomicsFoxl1-Cre-marked Adult Hepatic Progenitors Have Clonogenic and Bi-Lineage Differentiation Potential - Time Course
The winged helix transcription factor Foxl1 is a marker for progenitor cells and their descendants in the mouse liver in vivo. Here, we purify progenitor cells from Foxl1-Cre; RosaYFP mice and evaluate their proliferative and differentiation potential in vitro. Treatment of Foxl1-Cre; RosaYFP mice w...
ORGANISM(S): Mus musculus 
2011-05-01 | E-GEOD-28890 | biostudies-arrayexpress
UnknownThyroid hormone suppresses medulloblastoma progression through promoting terminal differentiation of tumor cells.
Not available
S-EPMC11565524 | biostudies-literature
TranscriptomicsExpression profiling of FOXK2 depletion by siRNA
Expression profiling was done of FOXK2 depletion by siRNA transfection. This was done on the human osteosarcoma U2OS cell line (which stably expresses FOXK2).
ORGANISM(S): Homo sapiens 
2011-11-03 | E-MEXP-3106 | biostudies-arrayexpress
ProteomicsEffect of parkin insufficiency on turnover rates of liver and striatal synaptic mitochondrial proteins
Using longitudinal metabolic labeling in a knock-out mouse model we assessed the effects of parkin insufficiency on the half-lives of mitochondrial proteins in vivo.
ORGANISM(S): Mus musculus (Mouse) 
2023-06-16 | PXD037993 | Pride
Striatal synapatic Mitophagy Parkinson’s disease Mouse Liver Mitochondria Parkin Neurodegeneration Topograph Half-life 
TranscriptomicsExpression profiling of exposure to phorbol myristate acetate - PMA and FOXK2 depletion with siRNA
Expression profiling was done of exposure to phorbol myristate acetate -PMA and FOXK2 depletion by siRNA transfection. This was done on the human osteosarcoma U2OS cell line which stably expresses FOXK2. PMA is an inducer of AP1 activity.
ORGANISM(S): Homo sapiens 
2011-11-03 | E-MEXP-3107 | biostudies-arrayexpress
UnknownA Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2.
Not available
S-EPMC7437481 | biostudies-literature
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