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ProteomicsProtein turnover analysis in Salmonella Typhimurium during infection by dynamic SILAC, Topograph and quantitative proteomics
Protein turnover affects protein abundance and phenotypes. Comprehensive investigation of protein turnover dynamics has the potential to provide substantial information about gene expression. Here we report a large-scale protein turnover study in Salmonella Typhimurium during infection by quantitati...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
2022-05-17 | PXD033623 | Pride
Proteomics Salmonella typhimurium Dynamic silac Protein turnover 
UnknownTopograph, a software platform for precursor enrichment corrected global protein turnover measurements.
Not available
S-EPMC3494182 | biostudies-literature
ProteomicsEffect of parkin insufficiency on turnover rates of liver and striatal synaptic mitochondrial proteins
Using longitudinal metabolic labeling in a knock-out mouse model we assessed the effects of parkin insufficiency on the half-lives of mitochondrial proteins in vivo.
ORGANISM(S): Mus musculus (Mouse) 
2023-06-16 | PXD037993 | Pride
Striatal synapatic Mitophagy Parkinson’s disease Mouse Liver Mitochondria Parkin Neurodegeneration Topograph Half-life 
ProteomicsAn Approach to Measuring Protein Turnover in Human Induced Pluripotent Stem Cell Organoids by Mass Spectrometry
Patient-derived organoids from induced pluripotent stem cells have emerged as a model for studying human diseases beyond conventional two-dimensional (2D) cell culture. As such, the development of robust methods to study global proteostasis and protein turnover in organoids will remain essential as ...
ORGANISM(S): Homo sapiens (Human) 
2024-06-16 | PXD032169 | Pride
Midbrain organoid Midbrain Silac Half-life determination Turnover D3-leucine Topograph Organoid 
UnknownCriteria-based curation of a therapy-focused compendium to support treatment recommendations in precision oncology.
Not available
S-EPMC8222322 | biostudies-literature
UnknownHomeostasis of functional maps in active dendrites emerges in the absence of individual channelostasis.
Not available
S-EPMC4035944 | biostudies-literature
UnknownPolarization induced control of optical trap potentials in binary liquids.
Not available
S-EPMC6345749 | biostudies-literature
UnknownAndreev Molecule in Parallel InAs Nanowires.
Not available
S-EPMC8517978 | biostudies-literature
ProteomicsATF4-Mediate Changes in Protein Turnover During Age-Related Skeletal Muscle Atrophy
Age-related skeletal muscle atrophy is a debilitating condition that has significant negative impacts on health and quality of life. Despite broad clinical impact, the molecular basis of age-related skeletal muscle atrophy is not well understood. Here, we determined protein turnover rates in skeleta...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
MSV000088083 | MassIVE
UnknownGate-Controlled Supercurrent in Epitaxial Al/InAs Nanowires.
Not available
S-EPMC8631737 | biostudies-literature
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