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TranscriptomicsRecruitment of FOXP1 to target genes in diffuse large B-cell lymphoma (DLBCL) cells
Identification of FOXP1 target genes in the OCI-Ly1 DLBCL cell line by ChIP-on-chip Three replicates of the FOXP1 ChIP-on-chip were performed in the OCI-Ly1 cells
ORGANISM(S): Homo sapiens 
2013-05-03 | E-GEOD-44243 | biostudies-arrayexpress
TranscriptomicsGene expression in human umbilical cord endothelial cells following FoxP1 knockdown
To search for genes regulated by the transcription factor Forkhead box Protein P1 (FoxP1) in endothelial cells, we transfected human umbilical cord endothelial cells (HUVECs) with a combination of three siRNA oligonucleotides directed against human FoxP1 . Human umbilical vein endothelial cells (HU...
ORGANISM(S): Homo sapiens 
2013-11-12 | E-GEOD-32968 | biostudies-arrayexpress
TranscriptomicsFOXP1 orchestration of ASD-relevant signaling pathways.
Mutations in the gene encoding the transcription factor forkhead box P1 or FOXP1 occur in patients with neurodevelopmental disorders, including autism. However, the function of FOXP1 in the brain remains mostly unknown. Here, we identify the gene expression program regulated by FoxP1 in both human n...
ORGANISM(S): Homo sapiens 
2015-10-26 | E-GEOD-62718 | biostudies-arrayexpress
TranscriptomicsThe role of Foxp1/4 in lung development
Foxp1/4 transcription factors are conserved transcriptional repressors expressed in overlapping patterns during lung development as well as in the adult lung. However, the role of Foxp1/4 in development and homeostasis of the pseudostratified epithelium of the proximal airways and trachea is unknown...
ORGANISM(S): Mus musculus 
2012-08-01 | E-GEOD-34584 | biostudies-arrayexpress
ProteomicsHuman nasopharyngeal cancer cell HONE1 FOXP1 immunoprecipitates LC-MS
Identification of peptides matching to LCK in FOXP1 immunoprecipitates from HONE1 cells by mass spectrometry
ORGANISM(S): Homo sapiens (Human) 
2022-04-04 | PXD031014 | Pride
Human Foxp1 Nasopharyngeal cancer cell 
GenomicsFoxp1 developing neocortex (scATAC-Seq)
Foxp1 developing neocortex (scATAC-Seq)
PRJNA1112381 | ENA
GenomicsFoxp1 developing neocortex (snRNA-Seq)
Foxp1 developing neocortex (snRNA-Seq)
PRJNA1112386 | ENA
TranscriptomicsGene expression profiling of FOXP1-silenced diffuse large B-cell lymphoma (DLBCL) cell lines
To identify differentially expressed genes regulated by FOXP1 in DLBCL cells via gene expression profiling of GCB-DLBCL (DB, K422) and ABC-DLBCL (OCI-Ly3, HBL-1) cell lines treated with siRNA targeting FOXP1 or non-silencing siRNA control. Two GCB-DLBCL (DB, K422) and two ABC-DLBCL (OCI-Ly3, HBL-1) ...
ORGANISM(S): Homo sapiens 
2015-10-27 | E-GEOD-71526 | biostudies-arrayexpress
TranscriptomicsAlpha-synuclein deficiency affects brain Foxp1 expression and ultrasonic vocalization
Alpha-synuclein is an abundant protein implicated in synaptic function and plasticity, but the molecular mechanism of its action is not understood. Missense mutations and gene duplication/triplication events result in Parkinson's disease, a neurodegenerative disorder of old age with impaired movemen...
ORGANISM(S): Mus musculus 
2010-07-21 | E-GEOD-19534 | biostudies-arrayexpress
GenomicsThe forkhead transcription factor FOXP1 profile in B-cells and B-cell lymphoma cell lines
Expression of the forkhead transcription factor FOXP1 is essential for early B cell development, whereas downregulation of FOXP1 at the germinal center (GC) stage is required for GC B cell function. Aberrantly high FOXP1 expression is frequently observed in diffuse large B cell lymphoma (DLBCL) and ...
ORGANISM(S): Homo sapiens 
2015-05-19 | E-GEOD-69009 | biostudies-arrayexpress
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