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MetabolomicsMulti-Omics and Integrated Network Analyses Reveal New Insights into the Systems Relationships between Metabolites, Structural Genes, and Transcriptional Regulators in Developing Grape Berries (Vitis vinifera L.) Exposed to Water Deficit (Volatile organic compounds; SPME-GC-MS assay)

Grapes are one of the major fruit crops and they are cultivated in many dry environments. This study comprehensively characterizes the metabolic response of grape berries exposed to water deficit at different developmental stages. Increases of proline, branched-chain amino acids, phenylpropanoids...

2021-08-16 | MTBLS982 | MetaboLights
MetabolomicsTranscriptome and metabolite profiling reveals that prolonged drought modulates the phenylpropanoid and terpenoid pathway in white grapes (Vitis vinifera L.) (Volatile organic compounds; SPME-GC-MS assay)

BACKGROUND: Secondary metabolism contributes to the adaptation of a plant to its environment. In wine grapes, fruit secondary metabolism largely determines wine quality. Climate change is predicted to exacerbate drought events in several viticultural areas, potentially affecting ...

2021-08-16 | MTBLS892 | MetaboLights
MetabolomicsTranscriptome and metabolite profiling reveals that prolonged drought modulates the phenylpropanoid and terpenoid pathway in white grapes (Vitis vinifera L.) (Phenolics; UPLC-MS/MS assay)

BACKGROUND: Secondary metabolism contributes to the adaptation of a plant to its environment. In wine grapes, fruit secondary metabolism largely determines wine quality. Climate change is predicted to exacerbate drought events in several viticultural areas, potentially affecting ...

2019-04-07 | MTBLS897 | MetaboLights
MetabolomicsMulti-Omics and Integrated Network Analyses Reveal New Insights into the Systems Relationships between Metabolites, Structural Genes, and Transcriptional Regulators in Developing Grape Berries (Vitis vinifera L.) Exposed to Water Deficit (Phenolics; UPLC-MS/MS assay)

Grapes are one of the major fruit crops and they are cultivated in many dry environments. This study comprehensively characterizes the metabolic response of grape berries exposed to water deficit at different developmental stages. Increases of proline, branched-chain amino acids, phenylpropanoids...

2019-04-07 | MTBLS898 | MetaboLights
TranscriptomicsIdentification of a DNA methylation signature in blood from subjects affected by Down syndrome
Down syndrome is characterized by a wide spectrum of clinical signs, which include cognitive and endocrine disorders and haematological abnormalities. Although it is well established that the causative defect of Down syndrome is the trisomy of chromosome 21, the molecular bases of Down syndrome phen...
ORGANISM(S): Homo sapiens 
2015-03-03 | E-GEOD-52588 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of human lymphoblastoid cell lines
Human lymphoblastoid cell lines (EBV-immortalised B cells, LcL) obtained from subjects of different age (young 28-40 years, centenarians >95 years) were analysed for gene expression at basal culture conditions and after 48 hours of serum starvation. Lymphoid B cells from centenarians were more resis...
ORGANISM(S): Homo sapiens 
2011-07-29 | E-GEOD-31040 | biostudies-arrayexpress
Genomicsena-DATASET-ErasmusMC-30-07-2021-14:00:05:691-768 - samples
Intellance-2: TruSight Tumor 170 panel based DNA-seq
EGAD00001007945 | EGA
Genomicsena-DATASET-ErasmusMC-30-07-2021-13:54:47:012-763 - samples
Intellance-2: rRNA-minus RNA-seq
EGAD00001007943 | EGA
Genomicsena-DATASET-ErasmusMC-30-07-2021-13:58:26:615-766 - samples
Intellance-2: TruSight Tumor 170 panel based RNA-seq
EGAD00001007944 | EGA
GenomicsIntellance-2: omics data on recurrent glioblastoma patients participating in the Intellance-2 clinical trial, prior to treatment.
This study contains omics data from patients from the Intellance-2 clinical trial, in which effectiveness of ABT414 in EGFR amplified recurrent glioblastoma patients was tested. Patients were randomly assigned to one of three arms: (1) standard of care treatement (TMZ or CCNU), (2) Only ABT414 and (...
EGAS00001005437 | EGA
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