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ProteomicsDppa2/4 target chromatin bivalency enabling multi-lineage commitment
Epigenetic priming factors establish a permissive epigenetic landscape which is not required until a later developmental or physiological time point, temporally uncoupling the presence of these factors with their phenotypic effects. One classic example of epigenetic priming is in the context of biva...
ORGANISM(S): Mus musculus (Mouse) 
2020-05-26 | PXD014981 | Pride
Qplex rime Epigenetic priming Compass Bivalency Development Trithorax 
ProteomicsEpendymoma instructs cranial haematopoiesis and immunotolerance
ZFTA-RELA ependymoma presents a significant clinical challenge due to the lack of effective treatments, driving the need to explore novel immunotherapeutic strategies. Recent studies have identified the skull bone marrow as a source of meningeal immune cells critical for central nervous system (CNS)...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-01 | PXD058239 | Pride
Immune surveillance Skull bone marrow Csf Hematopoiesis Regulatory t cell Childhood brain tumour Ependymoma 
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