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UnknownFemale Estrogen-Related Factors and Incidence of Basal Cell Carcinoma in a Nationwide US Cohort.
Not available
S-EPMC4669591 | biostudies-literature
TranscriptomicsGene expression profiles of LPS-stimulated RAW264.7 macrophages overexpressing Tbc1d23 novel innate immune gene
We previously identified Tbc1d23 as a candidate novel regulator of innate immunity using comparative genomics RNAi screens in C. elegans and mouse macrophages. Using mice with an engineered knockout mutation in Tbc1d23 and macrophages engineered to overexpress Tbc1d23, we now show that Tbc1d23 is a ...
ORGANISM(S): Mus musculus 
2012-04-03 | E-GEOD-30840 | biostudies-arrayexpress
TranscriptomicsA Methodology for Utilization of Predictive Genomic Signatures in FFPE Samples
Purpose: Gene expression signatures developed to measure the activity of oncogenic signaling pathways have been used to dissect the heterogeneity of tumor samples and to predict sensitivity to various cancer drugs that target components of the relevant pathways, thus potentially identifying therapeu...
ORGANISM(S): Homo sapiens 
2011-06-24 | E-GEOD-29598 | biostudies-arrayexpress
TranscriptomicsSpecific Inflammatory Stimuli Lead to Distinct Platelet Responses in mice and Humans
Different inflammatory stimuli contribute to the formation of atherosclerosis. It is hypothesized that although the end result is the same - plaque formation in arterial vessels - the pathogenesis is dependent on the etiology. In particular, platelets will respond differently depending on the inflam...
ORGANISM(S): Mus musculus 
2016-05-13 | E-GEOD-68835 | biostudies-arrayexpress
UnknownInvestigating the performance of 24-h urinary sucrose and fructose as a biomarker of total sugars intake in US participants - a controlled feeding study.
Not available
S-EPMC8326031 | biostudies-literature
TranscriptomicsCharacterization of the platelet transcriptome by RNA sequencing in patients with acute myocardial infarction.
Recent technological advances have made transcriptome sequencing (RNA-seq) possible in cells with low RNA copy number including platelets. Resulting studies have used RNA-seq in platelets isolated from healthy individuals to characterize the platelet transcriptome. However, platelets, possibly throu...
ORGANISM(S): Homo sapiens 
2015-09-15 | E-GEOD-65705 | biostudies-arrayexpress
UnknownChanges in late-life assistance networks for Black and White older adults during the COVID-19 pandemic.
Not available
S-EPMC11654626 | biostudies-literature
TranscriptomicsRNA expression at chromosome 8q24 in human colon
An inherited variant on chromosome 8q24, rs6983267, is significantly associated with cancer pathogenesis. We present evidence that this region is a transcriptional enhancer, that the risk region physically interacts with the MYC proto-oncogene, and that the alleles of rs6983267 differentially bind t...
ORGANISM(S): Homo sapiens 
2010-05-18 | E-GEOD-16228 | biostudies-arrayexpress
GenomicsEpstein-Barr Virus Exploits Intrinsic B-Lymphocyte Transcription Programs to Achieve Immortal Cell Growth
Epstein-Barr Virus Nuclear Antigen 2 (EBNA2) gene regulation through the cell RBPJ transcription factor (TF) is essential for conversion of resting B-lymphocytes (RBLs) into Lymphoblastoid Cell Lines (LCLs). ChIP-seq investigation of EBNA2 and RBPJ sites in LCL DNA found EBNA2 at 5151 and RBPJ at 10...
ORGANISM(S): Homo sapiens 
2011-07-01 | E-GEOD-29498 | biostudies-arrayexpress
UnknownDifferential and shared genetic effects on kidney function between diabetic and non-diabetic individuals.
Not available
S-EPMC9192715 | biostudies-literature
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