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TranscriptomicsTranscription profiling of human CD8 naive (TN), central memory (TCM), effector memory (TEM), and effector memory RA (TEMRA) T cells
Memory T cells are heterogeneous in terms of their phenotype and functional properties. We investigated the molecular profiles of human CD8 naïve (TN), central memory (TCM), effector memory (TEM), and effector memory RA (TEMRA) T cells using gene expression microarrays and phospho-protein-specific i...
ORGANISM(S): Homo sapiens 
2005-01-01 | E-TABM-40 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human embryonic kidney cells expressing apoptosis inducing proteins, time series
Three apoptosis inducing proteins, ACO1, STK3 and XBP1 were discovered in a previous reverse transfection screen. HEK293T cells were harvested and RNA extracted from the cells after over-expression of these 3 proteins at 12, 24 and 48 hours. A positive apoptosis inducer staurosporine and a negative ...
ORGANISM(S): Homo sapiens 
2005-09-05 | E-MEXP-421 | biostudies-arrayexpress
TranscriptomicsUterine stromal cell_cultured with uNK conditioned Medium
The endometrium contains a distinct population of immune cells consisting of 70% natural killer (NK) cells that undergo cyclic changes during the menstrual cycle. However, how these uterine NK (uNK) cells interact with uterine stromal cells (SC) remains unclear. We therefore investigated the paracri...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-9718 | biostudies-arrayexpress
TranscriptomicsMaking Safety Decisions for a Sunscreen Active Ingredient Using Next-Generation Risk Assessment: Benzophenone-4 Case Study
High throughput transcriptomics using the TempO-Seq (TM) platform for dose response modelling of 3 different cell lines treated with the compound Benzophenone-4 as part of case study to explore the application of Next Generation Risk Assessment approaches for a sunscreen active ingredient. The data ...
ORGANISM(S): Homo sapiens 
2025-07-31 | E-MTAB-15138 | biostudies-arrayexpress
TranscriptomicsOverexpression of non-degradable SAS-6 KEN box mutant in RPE-1 cells
Stable clones of RPE-1 cells expressing tetracycline-inducible wild type SAS-6 or SAS-6ND were obtained via lentiviral gene transduction with the pLVX tet-on Advanced inducible gene expression system (Clontech). Stable expressors were derived by selection with 5 μg/mL puromycin (Sigma-Aldrich, UK). ...
ORGANISM(S): Homo sapiens 
2025-01-27 | E-MTAB-13783 | biostudies-arrayexpress
TranscriptomicsAre Non-animal Systemic Safety Assessments Protective: A Toolbox and Workflow
High throughput transcriptomics using the TempO-Seq (TM) platform for dose response modelling of 3 different cell lines treated with multiple compounds as part of a study to generate a toolbox and workflow for non-animal safety assessments. The data generated here was produced as one part of a toolb...
ORGANISM(S): Homo sapiens 
2025-09-15 | E-MTAB-15258 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of HAstV1, HAstV4, MLB1, MLB2 and VA1 astrovirus infection in cell culture
The purpose of the study was to investigate the dynamics of viral RNA production during astrovirus infection. Caco-2 cells were infected at MOI 5 with HAstV1, HAstV4 or VA1; Huh7.5.1 cells were infected at MOI 5 with MLB1 or MLB2. Cells were harvested at 6, 12, 18, 24 (HAstV1) or 24 (HAstV4, MLB1, M...
ORGANISM(S): Homo sapiens 
2026-04-17 | E-MTAB-16460 | biostudies-arrayexpress
UnknownIdentification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus.
Not available
S-EPMC4962376 | biostudies-literature
UnknownFine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer's disease.
Not available
S-EPMC3036586 | biostudies-literature
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
Not available
S-EPMC12056793 | biostudies-literature
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