Friedrichsen Martin M

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Transcriptomics (2)
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Homo sapiens (2)
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biostudies-arrayexpress (2)
pride (1)

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Mass Spectrometry (1)
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2014 (1)
2012 (1)
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Transcription profiling by array (1)
Methylation profiling by array (1)

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2014 (1)
2012 (1)

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Diabetes & Metabolism, Garvan Institute of Medical Research (1)

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Quantitative proteomic analysis of the human extracellular vesicle proteome reveals a novel mechanism for tissue cross-talk during exercise

Exercise stimulates the release of a plethora of molecules into the circulation, supporting the concept that inter-tissue signaling proteins are important mediators of adaptations to exercise. Recognising that many circulating proteins might be packaged in extracellular vesicles (EV), we employed qu...

ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse)

2018-01-10 | PXD006501 | Pride

Differential regulation of microRNAs in skeletal muscle from monozygotic twins discordant for type 2 diabetes

Analysis of microRNA expression in vastus lateralis muscle biopsies from 11 genetically identical twin pairs discordant for type 2 diabetes. This eliminates the influence of genotype and leads to the identification of microRNAs that are exclusively influenced by environmental (non-genetic) factors. ...

ORGANISM(S): Homo sapiens

2014-11-19 | E-GEOD-38835 | biostudies-arrayexpress

Genome-Wide Analysis of DNA Methylation Differences in Muscle and Fat from Monozygotic Twins Discordant for Type 2 Diabetes

Monozygotic twins discordant for type 2 diabetes constitute an ideal model to study environmental contributions to type 2 diabetic traits. We aimed to examine whether global DNA methylation differences exist in major glucose metabolic tissues from twelve 53–80 year-old monozygotic discordant twin pa...