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ProteomicsONGOING CHROMOSOMAL INSTABILITY ACROSS ANEUPLOID SUBTYPES OF CHILDHOOD B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA ASSOCIATES WITH DISEASE PROGRESSION
Chromosomal instability (CIN), defined as an increased occurrence of chromosome segregation errors during cell division, is a prominent form of genomic instability (Bakhoum and Avi Landau, 2017). It is the major cause of aneuploidy, an imbalanced complement of whole chromosomes or chromosome arms, w...
ORGANISM(S): Homo sapiens (Human) 
2023-09-15 | PXD042785 | Pride
Aneuploidy B-cell acute lymphoblastic leukemia Childhood b-all Chromosomal instability 
ProteomicsImmune response disfunction in chronic lymphocytic leukemia: Dissecting molecular mechanism by multipronged functional proteomics approaches. Crucial parameters for the evaluation of Immunopeptidomic analysis.
The main goal of the current project is to design and develop a multipronged functional proteomics strategy, with translation into the clinic, for deciphering all the microenvironment protein factors involved in the dysfunction of the immune system in MBLhi and CLL patients in order to understand th...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD038165 | Pride
Immunopeptidomics Immunopeptidome Lc-ms/ms 
ProteomicsOrder 28341 - Carla Miro Vinyals 2022-05-09
HeLa treated with IAA or NEM (Figure S3). Stable cell line expressing GALT1-HA-sCGrx1p sensor protein were treated with 20 mM NEM (A) or IAA (B) for 30 min at 37°C. The processed samples are anti-HA magnetic beads with the sensor protein captured from whole cell lysate.
ORGANISM(S): Homo sapiens (Human) 
2025-02-17 | PXD060873 | Pride
Human 
UnknownThe multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities.
Not available
S-EPMC9825158 | biostudies-literature
UnknownMulticentric randomized clinical trial to evaluate the long-term effectiveness of a motivational intervention against smoking, based on the information obtained from spirometry in primary care: the RESET study protocol.
Not available
S-EPMC4743363 | biostudies-literature
UnknownSARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.
Not available
S-EPMC8652887 | biostudies-literature
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