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Acute respiratory distress syndrome (ARDS) is a severe and complex critical illness, characterized by its heterogeneous clinical presentation, making accurate clinical definition and effective treatment challenging. We hypothesized that advanced molecular analyses of matched plasma and bronchial alv...
ORGANISM(S): Homo sapiens (Human) 
2026-02-16 | PXD060437 | Pride
Silver nanoparticles (AgNPs) are widely used nanomaterials in both commercial and clinical biomedical applications, but the molecular mechanisms underlying their activity remain elusive. In this work we profiled proteomics and redox proteomics changes induced by AgNPs in two lung cancer cell lines:...
ORGANISM(S): Homo sapiens (Human) 
2021-04-01 | PXD021493 | Pride
The catalytic activity of Abl family kinases is tightly regulated in cells by a complex set of intra- and intermolecular interactions and post-translational modifications. Abl family kinases are activated by diverse cellular stimuli, one of them being receptor tyrosine kinase signaling. For example,...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD025896 | Pride
Redox signaling and cardiac function are tightly linked. Still, it is largely unknown which specific protein targets are affected by reactive oxygen species (ROS) that underly the impaired inotropic effect in oxidative stress. Here, we combined a new chemogenetic mouse model (HMC HyPer-DAO transgeni...
ORGANISM(S): Mus musculus (Mouse) 
2025-07-15 | PXD033119 | Pride
Quantitative redox proteomics analysis was performed using the SCC-61/rSCC-61 matched model system of radiation resistance in human head and neck squamous cell carcinoma.
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD029053 | Pride
Redox signaling and cardiac function are tightly linked. Still, it is largely unknown which specific protein targets are affected by reactive oxygen species (ROS) that underly the impaired inotropic effect in oxidative stress. Here, we combined a new chemogenetic mouse model (HMC HyPer-DAO transgeni...
ORGANISM(S): Mus musculus (Mouse) 
2023-04-21 | PXD037987 | Pride
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