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ProteomicsGABA, glucose and insulin orchestrate CD4+ T cells effector functions
Metabolic programs of immune cells are closely linked to their effector functions , where physiological molecules provide environmental cues and guidance. Exactly how it happens is still being unraveled. Insulin maintains normal blood glucose levels and glucose is themain source of energy and a prec...
ORGANISM(S): Homo sapiens (Human) 
2024-08-10 | PXD041654 | Pride
Cd4 Gaba 
ProteomicsSpectrin-beta 2 facilitates the selective accumulation of GABAA receptors at somatodendritic synapses
Fast synaptic inhibition is dependent on targeting specific GABAAR subtypes to dendritic and axon initial segment (AIS) synapses. Synaptic GABAARs are typically assembled from 1-3, and subunits. Here, we isolate distinct GABAARs from the brain and interrogate their composition using quantitative pr...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-10 | PXD038703 | Pride
Ais Gaba a receptors Spectrins 
TranscriptomicsExpression analysis of superior cervical ganglion from backcrossed TH-MYCN transgenic mice
Neuroblastoma susceptibility in TH-MYN mice is heavily influence by mouse strain background. We have combined linkage analysis of tumor susceptibility with expression QTL analysis of superior cervical ganglia (pure peripheral symptathetic nervous tissue) to identify genes underlying tumor formation...
ORGANISM(S): Mus musculus 
2015-01-30 | E-GEOD-59675 | biostudies-arrayexpress
TranscriptomicsExpression changes in IC GABA receptors in the auditory midbrain of young adult and aging presbycusis mice.
We performed a microarray analysis of auditory midbrain (inferior colliculus, IC) mRNA from young adult CBA mice (controls) with good hearing, middle aged (MA) with good hearing, and old mild (MP) and severe (SP) presbycusic CBA mice. Fold Change data derived from RMA normalization revealed that the...
ORGANISM(S): Mus musculus 
2013-08-06 | E-GEOD-49522 | biostudies-arrayexpress
UnknownGamma-aminobutyric acid (GABA) can affect physiological processes in preimplantation embryos via GABAA and GABAB receptors.
Not available
S-EPMC10354355 | biostudies-literature
UnknownThe desensitization pathway of GABAA receptors, one subunit at a time.
Not available
S-EPMC7585415 | biostudies-literature
UnknownComposition of the GABA(A) receptors of retinal dopaminergic neurons.
Not available
S-EPMC6782470 | biostudies-literature
UnknownStimulation of TM3 Leydig cell proliferation via GABA(A) receptors: a new role for testicular GABA.
Not available
S-EPMC416489 | biostudies-literature
UnknownGenetic and Molecular Regulation of Extrasynaptic GABA-A Receptors in the Brain: Therapeutic Insights for Epilepsy.
Not available
S-EPMC5771312 | biostudies-literature
UnknownRundown of GABA type A receptors is a dysfunction associated with human drug-resistant mesial temporal lobe epilepsy.
Not available
S-EPMC1257725 | biostudies-literature
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