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ProteomicsQuantitative proteomic analysis of apical interacting partners of canine galectin 8
Primary cilium is a specialized sensory organelle protruding from apical surface of most cells that transmits environmental information into cells. Its length is tightly controlled by various mechanisms such as the frequency or the cargo size of the intraflagellar transport trains which deliver the ...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2023-11-25 | PXD038021 | Pride
Transition zone Primary cilia Galectin 8 Lipid raft 
ProteomicsGalectin-8 facilitates B cell responses to surface-tethered antigens by promoting antigen extraction at the B cell synapse
Complete activation of B cells relies on their capacity to extract surface-tethered 35  antigens at the immune synapse by either exerting mechanical forces or promoting 36  their proteolytic degradation through lysosome secretion. Whether antigen extraction 37  can be tuned by local cues originating...
ORGANISM(S): Mus musculus (Mouse) 
2018-12-14 | PXD011522 | Pride
B-lymphocytes Processing and presentation Polarity Mouse immunization Immune synapse Antigen extraction Galectin-8 
GenomicsAblation of the Mammalian Lectin Galectin-8 Induces Bone Defects in Mice
Ablation of the Mammalian Lectin Galectin-8 Induces Bone Defects in Mice
PRJNA417476 | ENA
GenomicsEffect of Galectin-8 treatment on gene expression of human peripheral blood mononuclear cells
Effect of Galectin-8 treatment on gene expression of human peripheral blood mononuclear cells
PRJNA1020777 | ENA
GenomicsGalectin-8 induces functional disease markers in human osteoarthritis and cooperates with galectins-1 and -3.
Galectin-8 induces functional disease markers in human osteoarthritis and cooperates with galectins-1 and -3.
PRJNA545084 | ENA
TranscriptomicsEffect of Galectin-8 treatment on gene expression of human peripheral blood mononuclear cells
Galectin-8 is an identified ligand of LILRB4, which is an immune checkpoint receptor expressed on monocytic cells.Human PBMCs were treated with or without Galectin-8 to test transcriptome alteration. We then performed gene expression profiling analysis using data obtained from RNA-seq of 3 replicate...
ORGANISM(S): Homo sapiens 
2023-12-13 | GSE243947 | GEO
UnknownGalectin-8 Contributes to Human Trophoblast Cell Invasion.
Not available
S-EPMC11431856 | biostudies-literature
TranscriptomicsGalectin-8 induces functional disease markers in human osteoarthritis and cooperates with galectins-1 and -3.
The reading of glycan-encoded signals by tissue lectins is considered a major route of the flow of biological information in many (patho)physiological processes. The arising challenge for current research is to proceed from work on a distinct protein to family-wide testing of lectin function. Having...
ORGANISM(S): Homo sapiens 
2021-02-17 | GSE131822 | GEO
GenomicsThe role of Galectin-8 in mouse stomach maturation
The role of Galectin-8 in mouse stomach maturation
PRJNA1430404 | ENA
UnknownGalectin-8 modulates human osteoclast activity partly through isoform-specific interactions.
Not available
S-EPMC10895193 | biostudies-literature
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