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We compared the mRNAs expression profile of HeLa cells between two phases of the mitotic cell cycle: S and G2/M phases. Results provide insight into the regulation of transcript levels during mitotic cell cycle progression. HeLa cells were synchronized with double thymidine blockade (12 hours with ...
ORGANISM(S): Homo sapiens 
We compared the poly(A) tail length status of mRNAs of HeLa cells between two phases of the mitotic cell cycle: S and G2/M phases. Hundreds of mRNAs were found to be regulated by changes in their poly(A) tail length during mitotic cell cycle in a phase specific manner. Many of these differentially p...
ORGANISM(S): Homo sapiens 
To validate our results on Foxf2 related Tie2 signaling and explore their transferability to human cells, we studied human iPSC-derived endothelial cells (iECs). FOXF2KO and WT iECs (González-Gallego et al., in preparation) were treated with AKB-9778 or vehicle and assessed by proteomics. Similar to...
ORGANISM(S): Homo sapiens (Human) 
2025-09-02 | PXD051855 | Pride
The aim of the project was to systematically analyze the mechanism mediated by the Drs2 ISTTK motif in yeast, located in the N-terminal tail of the protein. Upon a GFP-specific pulldown, we carried-out a comparative analysis between the interactome of Drs2-GFP and drs2-5A-GFP (ISTTK>AAAAA) to identi...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-03-08 | PXD038527 | Pride
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