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The mechanisms responsible for weight loss-induced improvement in insulin sensitivity are partially understood. Greater insight can now be achieved through deep phenotyping and data integration. Here, we used an integrative approach to investigate associations between changes in insulin sensitivity ...
2021-02-11 | MTBLS653 | MetaboLights
A novel approach combined nucleolar beacon with proximity labeling to obtain the nucleolar proteome. These techniques offer effective tools for investigating nucleolar functions in living cells and present a potential application method for drug delivery.
ORGANISM(S): Homo sapiens (Human) 
2025-06-23 | PXD059125 | Pride
Hypothalamic dysfunction is a key pathological factor in inflammation-associated depression. In the present study, isobaric tags for relative-absolute quantitation (iTRAQ) combined with mass spectrometry were employed to detect the proteomes in the hypothalamus of the lipopolysaccharide (LPS)-induce...
ORGANISM(S): Mus musculus (Mouse) 
2020-01-09 | PXD016040 | Pride
Mannheimia haemolytica (M. haemolytica) cause mastitis in sheep, acute sepsis in newborn lambs, and co-infections with various pathogens, leading to bovine respiratory disease syndrome (BRDS), these infections have resulted in significant economic losses to both domestic and international farming in...
ORGANISM(S): Mannheimia haemolytica M42548 
2025-06-30 | PXD064633 | Pride

The complex stripes and patterns of insects play key roles in behavior and ecology. However, the fine-scale regulation mechanisms underlying pigment formation and morphological divergence remain largely unelucidated. Here we demonstrated that imaginal disc growth factor (IDGF) maintains cuticle s...

2020-09-20 | MTBLS1825 | MetaboLights
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