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Aflatoxin M1 (AFM1) is a common mycotoxin in dairy milk and it is typically concurrently present with other mycotoxins that may represent a threat for food safety. However, knowledge on how AFM1, alone or in combination with other mycotoxins may affect human intestinal epithelial integrity remain to...
ORGANISM(S): Homo sapiens (Human) 
2018-08-08 | PXD009437 | Pride
In order to further explore the expression of proteins in RSV-infected macrophages, RSV type-L19 was used to stimulate RAW264.7 cells, and then mass spectrometry was conducted to detect the expression of different proteins after RSV infection. The results showed that there were different expression ...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-26 | PXD042041 | Pride
Lung cancer is the leading cause of cancer-related deaths worldwide. Chemotherapy kills most cancer cells, however, the residual cells enter into dormant state. The dormant cancer cells can be reactivated under specific circumstances. Tumor-derived exosomes are the main mediators of tumorigenesis. W...
ORGANISM(S): Homo Sapiens 
2022-10-17 | PXD037475 |
The hippocampus and entorhinal cortex are the earliest areas affected by AD pathology, which are related to early memory loss in patients. The hippocampus subfields are heterogeneous, with different order and degree affect by AD pathology. Studying the molecular changes may explain the difference, a...
ORGANISM(S): Homo Sapiens 
2021-07-16 | PXD027380 |
The size of plant lateral organs is determined by well-coordinated cell proliferation and cell expansion. Here, we report that miR159, an evolutionarily conserved microRNA, plays an essential role in regulating cell division in rose (Rosa hybrida) petals by modulating cytokinin catabolism. We uncove...
ORGANISM(S): Rosa Hybrid Cultivar 
2023-10-18 | PXD046197 |
The abnormal induction of macroautophagy/autophagy, a highly conserved lysosome-based degradation pathway, has been postulated as a major toxicity of nanomaterials, whereas little is known on the exact molecular mechanisms. Here, we treated mammalian cells with 16 nm silica nanoparticles (SiNPs), co...
ORGANISM(S): Rattus Norvegicus 
2019-12-01 | PXD012196 |
Oncolytic viruses (OVs) combined with radiotherapy (RT) have shown promise in clinical trials but remain limited by unsatisfactory efficacy. Key challenges include poor intravenous delivery, insufficient RT-induced DNA damage, and suboptimal anti-tumor immune responses. Herein, we developed a novel ...
ORGANISM(S): Homo Sapiens Mus Musculus 
2025-02-02 | PXD060493 |
The protein corona formed on the surface of nanomaterials is critical to understanding their biological behavior, as it is regulated by both the physicochemical properties of the nanomaterials and the physiological environment. The interplay between material synthesis characteristics, protein corona...
ORGANISM(S): Homo Sapiens 
2024-10-14 | PXD056769 |
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