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ProteomicsIdentify the specific binding partners of cytosolic TDP-43 WT and TDP-43ΔCR
To investigate how translation changed as a function of TDP-43 CR loss, mass spectrometry (MS) based approach was performed to monitor the dynamics of TDP-43-associated protein complexes in response to CR deletion using TDP-43 knockout HEK293 cells expressing strep tagged wild type TDP-43 (TDP-43WT)...
ORGANISM(S): Homo sapiens (Human) 
2022-05-20 | PXD027494 | Pride
Human cells Tdp-43 Cytosolic binding partners 
ProteomicsHSPA4 restrains transferrin in dopaminergic neurons to attenuate ferroptosis in a Parkinson’s disease model
Heat shock protein A4 (HSPA4) is a molecular chaperone belonging to the heat shock protein 70 (HSP70) family. This study aims to investigate the antiferroptotic effects of HSPA4 in a Parkinson’s disease (PD) model and explore the underlying mechanisms. Here we show that HSPA4 overexpression reduces ...
ORGANISM(S): Homo sapiens (Human) 
2025-10-20 | PXD067550 | Pride
Dopaminergic neurons Hspa4 Parkinson’s disease Ferroptosis Transferrin 
UnknownN-glycoform diversity of cellobiohydrolase I from Penicillium decumbens and synergism of nonhydrolytic glycoform in cellulose degradation.
Not available
S-EPMC3346090 | biostudies-literature
UnknownLactate-to-glucose ratio and short-term all-cause mortality in critically ill cirrhosis patients: a MIMIC-IV and eICU-CRD database study.
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S-EPMC12541970 | biostudies-literature
UnknownEvaluation of Optimal Diastolic Blood Pressure Range Among Adults With Treated Systolic Blood Pressure Less Than 130 mm Hg.
Not available
S-EPMC7890449 | biostudies-literature
UnknownRegional metastasis to anatomies beyond traditional neck dissection boundaries: a multi-institutional analysis focused on unconventional metastases in oral cancer patients.
Not available
S-EPMC7594434 | biostudies-literature
UnknownPositive regulation of the Shewanella oneidensis OmpS38, a major porin facilitating anaerobic respiration, by Crp and Fur.
Not available
S-EPMC4585640 | biostudies-literature
UnknownInterplay Between Liver Type 1 Innate Lymphoid Cells and NK Cells Drives the Development of Alcoholic Steatohepatitis.
Not available
S-EPMC9676399 | biostudies-literature
UnknownSorbus gongshanensis (Rosaceae), a new species from the Hengduan Mountains, China.
Not available
S-EPMC7093571 | biostudies-literature
UnknownA SNP in intron 8 of CD46 causes a novel transcript associated with mastitis in Holsteins.
Not available
S-EPMC4124149 | biostudies-literature
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