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UnknownInterleukin-18 genetic polymorphisms contribute differentially to the susceptibility to Crohn's disease.
Not available
S-EPMC4515852 | biostudies-literature
TranscriptomicsHigh-throughput Illumina Hiseq2000 seuqencing of small RNAs from Hevea brasiliensis PB260 and PB217 clones
MicroRNAs (miRNAs) are non-coding, short, single-stranded RNAs with essential roles in gene regulation in various organisms including higher plants. In contrast to the vast information on miRNAs from many economically important plants, almost nothing has been reported on the identification or analy...
ORGANISM(S): Hevea brasiliensis 
2012-04-02 | E-GEOD-35254 | biostudies-arrayexpress
MetabolomicsUPLC-QTOF-MS-Based Plasma Lipidomic Profiling Reveals Biomarkers for Inflammatory Bowel Disease Diagnosis
Identification of new biomarkers may help in the early diagnosis of inflammatory bowel disease (IBD). In this study, ultrahigh-performance liquid chromatography equipped with quadrupole time-of-flight mass spectrometry (UPLC-QTOF-MS) was used to analyze the untargeted lipidomics and compare plasma l...
2021-10-18 | MTBLS1183 | MetaboLights
ProteomicsHeat tolerance of pakchoi (Brassica rapa L. chinensis) to high temperature: physiological, transcriptomic, and proteomic perspectives
To elucidate the molecular mechanisms underlying heat stress tolerance in pakchoi, we investigated the physiological indicators and conducted comprehensive transcriptomic and proteomic profiling of leaves from a heat-tolerant pakchoi line.
ORGANISM(S): Brassica rapa subsp. chinensis 
2026-03-07 | PXD068141 | Pride
Heat-tolerance Brassica rapa sub. chinensis Transcriptomic Proteomic 
UnknownEffects of upadacitinib on enthesitis in patients with psoriatic arthritis: a post hoc analysis of SELECT-PsA 1 and 2 trials.
Not available
S-EPMC11534117 | biostudies-literature
GenomicsGenome-wide profiling of trimethylated histone H3 lysine 27 (H3K27me3) in wide-type, brm, clf, and brm clf mutant seedlings
By using ChIP-seq, we found that loss of BRM activity in developing seedlings leads to ectopic and increased H3K27me3 deposition at several hundred genes, indicating the critical role of BRM in preventing the inappropriate deposition of this histone mark. Removal of CLF in brm mutant could partciall...
ORGANISM(S): Arabidopsis thaliana 
2015-03-09 | E-GEOD-53620 | biostudies-arrayexpress
GenomicsBAF250a regulates nucleosome occupancy and histone modification in priming embryonic stem cell differentiation
BAF complex is one major group of chromatin remodeling factors in mammals. However, how BAF regulated nucleosomes and other histone modifications is not clear. Here we delete BAF250a, a major component in esBAF to study the nucleosome and histone changes in ESCs. We find that deletion of BAF250a lea...
ORGANISM(S): Mus musculus 
2015-08-03 | E-GEOD-59082 | biostudies-arrayexpress
GenomicsTOP1M-NM-1 functions on nucleosome density
DNA topoisomerases release supercoils in DNA introduced during replication or transcription. How DNA topoisomerases impact transcription in the context of eukaryotic chromatin is poorly understood. In this study, using a floral stem cell model in Arabidopsis, we uncovered a role of TOP1M-NM-1 in Pol...
ORGANISM(S): Arabidopsis thaliana 
2014-10-14 | E-GEOD-53950 | biostudies-arrayexpress
TranscriptomicsExpression data from Ler and TOP1a-2 inflorescences
DNA topoisomerases release supercoils in DNA introduced during replication or transcription. How DNA topoisomerases impact transcription in the context of eukaryotic chromatin is poorly understood. In this study, using a floral stem cell model in Arabidopsis, we uncovered a role of TOP1a in Polycomb...
ORGANISM(S): Arabidopsis thaliana 
2014-10-14 | E-GEOD-42403 | biostudies-arrayexpress
UnknownCompositional Analysis of Grape Berries: Mapping the Global Metabolism of Grapes.
Not available
S-EPMC11639774 | biostudies-literature
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