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ProteomicsStructural insights into dynamics of the BMV TLS aminoacylation
We performed Biotinylated RNA pull-down coupled with mass spectrometry, which enables the identification of TLS-binding proteins. Using in vitro synthesized BMV TLS and protein extracts derived from Nicotiana tabacum L.'s leaves, mass spectrometry results demonstrated the enrichment of ribosome-asso...
ORGANISM(S): 'nicotiana Tabacum' Yellowing Phytoplasma 
2024-11-13 | PXD057815 |
TranscriptomicsBone marrow gene expression of pediatric acute lymphoblastic leukemia (ALL)
Pediatric acute lymphoblastic leukemia (ALL) contains cytogenetically distinct subtypes that respond differently to cytotoxic drugs. Subtype classification can be also achieved through gene expression profiling. However, how to apply such classifiers to a single patient and correctly diagnose the di...
ORGANISM(S): Homo sapiens 
2009-08-19 | E-GEOD-17703 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of hrf1 transformed rice revealed crosstalk between disease resistance and drought tolerance mediated by Harpin
Harpin proteins from Gram-negative plant pathogenic bacteria can activate distinct signaling pathways and cause multiple effects in plants. In this document, we observed the transcriptome profile in transgenic NJH12 and wide type R109 using a customized 57 k rice cDNA microarray and found 225 differ...
ORGANISM(S): Oryza sativa 
2013-12-29 | E-GEOD-36661 | biostudies-arrayexpress
UnknownA Mettl16/m6A/Mybl2b/Igf2bp1 axis ensures cell cycle progression of embryonic hematopoietic stem and progenitor cells
Not available
S-SCDT-10_1038-S44318-024-00082-9 | biostudies-other
UnknownThioparib Inhibits Homologous Recombination Repair, Activates the Type-I IFN Response, and Overcomes Olaparib Resistance
Not available
S-SCDT-10_15252-EMMM_202216235 | biostudies-other
ProteomicsStructural insights into regulatory mechanism of RNA modification by human m6A-METTL associated complex
N6-methyladenosine (m6A) is the most abundant ribonucleotide modification among the eukaryotic messenger RNAs (mRNAs). The m6A “writer” is composed of an m6A-METTL complex (MAC), the catalytic subunit, and an m6A-METTL associated complex (MACOM), the regulatory subunit essential for the enzymatic ac...
ORGANISM(S): Homo Sapiens 
2022-06-23 | PXD028456 |
ProteomicsHuman HNF1A KI mice liver proteome analysis
Nonalcoholic fatty liver disease (NAFLD) is a pathological condition caused by excessive fat accumulation in liver. HNF1A is the pathogenic cause of hepatocellular adenoma and HCC. It is an important transcription factor in liver. We constructed a knock-in mice expressing a human dominant negative H...
ORGANISM(S): Mus Musculus 
2023-03-02 | PXD040561 |
ProteomicsAI-facilitated multi-omics reveal TRF-controlled propionylation in determining protein homeostasis
Firstly, we systematically identified rhythmically modified Kpr sites, through time-series propionylomic profiling of fly heads. Wild-type (WT) and per0 flies were entrained under light/dark cycles (LD) and then released into constant darkness (DD), respectively. On the first day of DD, whole heads ...
ORGANISM(S): Drosophila Melanogaster 
2023-03-20 | PXD040987 |
ProteomicsInteraction partners with NOP2/Sun RNA methyltransferase 2 (NSUN2) in gallbladder carcinoma
Proteins interacting with NSUN2 in gallbladder carcinoma (NOZ cell line)
ORGANISM(S): Homo Sapiens 
2019-03-20 | PXD013152 |
ProteomicsMicroglia and brain organoids
iPSC-derived microglia export cholesterol to neuronal cells in human brain organoids and promote their maturation
ORGANISM(S): Homo Sapiens (human) 
PXD042344 | JPOST Repository
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