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MetabolomicsComprehensive lipid analysis of green Arabica coffee beans by LC-HRMS/MS
Lipids play an important role in coffee bean development, coffee brew and in the effects of coffee on human health. They account for around 17% of the dry bean weight and encompass different classes and subclasses, mostly triacylglycerols (TAG) and a minor quantity of phospholipids (PL) and βN-alkan...
2021-11-19 | MTBLS1972 | MetaboLights
MetabolomicsA Novel Metabolic Signature To Predict the Requirement of Dialysis or Renal Transplantation in Patients with Chronic Kidney Disease
Identification of chronic kidney disease patients at risk of progressing to end-stage renal disease (ESRD) is essential for treatment decision-making and clinical trial design. Here, we explored whether proton nuclear magnetic resonance (NMR) spectroscopy of blood plasma improves the currently best ...
2019-07-26 | MTBLS798 | MetaboLights
Transcriptomicsarray-CGH on single blastomeres from day-4 human preimplantation fresh and frozen embryos
In total, 240 single blastomeres from nine top-quality day-4 embryos frozen at day 3 of development and four fresh top-quality day-4 embryos that had one-cell biopsy on day 3 for preimplantation genetic diagnosis (PGD) were collected. Blastomeres' DNA was amplified using SurePlex DNA Amplification S...
ORGANISM(S): Homo sapiens 
2013-04-05 | E-GEOD-39518 | biostudies-arrayexpress
MetabolomicsHif1α-Dependent Uncoupling Of Glycolysis Suppresses Tumor Cell Proliferation
Hypoxia-inducible factor-1α (HIF1α) attenuates mitochondrial activity while promoting glycolysis. Paradoxically, it remains unknown why lower glycolysis is compromised in human clear cell renal cell carcinomas (ccRCC), in which HIF1α acts a tumor suppressor by inhibiting cell autonomous proliferatio...
2024-03-15 | MTBLS8901 | MetaboLights
UnknownLeishmania infantum arginase: biochemical characterization and inhibition by naturally occurring phenolic substances.
Not available
S-EPMC6534257 | biostudies-literature
TranscriptomicsSingle-cell RNA and B cell receptor profiling of B cell response to SARS-CoV-2 vaccination
We generated single-cell transcriptomic and BCR sequencing data of B cells from peripheral blood samples taken from a SARS-CoV-2-antigen-naive cohort being vaccinated with the SARS-CoV-2 mRNA-1273 vaccine. Blood samples were collected at the baseline timepoint D-1 (i.e. one day prior to the initial ...
ORGANISM(S): Homo sapiens 
2026-05-08 | E-MTAB-16531 | biostudies-arrayexpress
Transcriptomicsarray-CGH on single blastomeres from day-3 human cleavage stage embryos
Seventy blastomeres from fourteen frozen-thawed supernumerary human preimplantation embryos were disassociated and genomic was amplified using Multiple Displacement Amplification. BAC array-CGH was performed on the amplified products. BAC array-CGH on single blastomeres amplified by Multiple Displac...
ORGANISM(S): Homo sapiens 
2012-10-15 | E-GEOD-34290 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA and BCR sequencing of naive B cells cultured in IgG class-switching polarising conditions
Naive B cells (CD27-IgD+) were obtained from 3 healthy controls and cultured in vitro under anti-IgM, CD40L and IFN-gamma to polarise class-switching towards IgG isotypes. Single-cell RNA and BCR sequencing libraries were prepared at Day 0 (before addition of stimuli), Day 3 and Day 6 of the cell cu...
ORGANISM(S): Homo sapiens 
2023-07-01 | E-MTAB-13050 | biostudies-arrayexpress
TranscriptomicsIdentification of copy number changes in cell lines of a vGPCR-driven mouse tumor model
Genomic DNA of KSHV-vGPCR-transformed tumor cell lines (vGPCR-BTC#1+#2), vGPCR-transformed 3T3 cell lines and a GFP-3T3 control cell line was cohybridized with normal BALB/c reference genomic DNA. gDNA of cell lines labeled with Cy3 gDNA of reference DNA labeled with Cy5
ORGANISM(S): Mus musculus 
2016-02-09 | E-MTAB-3394 | biostudies-arrayexpress
UnknownDo different foot types affect the 6-min walk test capacity of younths with Charcot-Marie-Tooth neuropathy ?
Not available
S-EPMC9101939 | biostudies-literature
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