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TranscriptomicsNucleosome Distribution Data for Methylphenidate Treatment
Jurkat T-leukemic cells at 0, 15, 45, and 240 minutes post MPH treatment. Chromatin structure depends highly on the position and density of nucleosomes in the genome. The distribution of these nucleosomes likely plays a critical role in all processes for which DNA is the template, including: gene ex...
ORGANISM(S): Homo sapiens 
2015-06-26 | E-GEOD-70292 | biostudies-arrayexpress
ProteomicsDNMT3A regulates megakaryocyte-biased HSC fate decisions
We characterized the role of the DNA methyltransferase DNMT3A in the fate decisions of murine megakaryocyte-biased HSCs and in the differentiation of megakaryocytes and platelets. In this experiment, we isolated washed platelets from 4 WT and 4 Dnmt3a+/– germline mice (2 males and 2 females per grou...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-09 | PXD055265 | Pride
Platelets Megakaryocytes Dna methylation Dnmt3a 
UnknownAll-dielectric scale invariant waveguide.
Not available
S-EPMC10590422 | biostudies-literature
UnknownPrimary angioplasty vs. fibrinolysis in very old patients with acute myocardial infarction: TRIANA (TRatamiento del Infarto Agudo de miocardio eN Ancianos) randomized trial and pooled analysis with previous studies.
Not available
S-EPMC3013200 | biostudies-literature
UnknownPlasma exchange therapy for the post COVID-19 condition: a phase II, double-blind, placebo-controlled, randomized trial.
Not available
S-EPMC11850642 | biostudies-literature
ProteomicsDimeric IgA specifically disables intracellular mutated oncodrivers
Despite their long half-life, therapeutic antibodies are considered ineffective against intracellular antigens due to their perceived inability to penetrate epithelial cells. Using recombinant antibodies targeting common mutations in oncogenes, we demonstrate that dimeric IgA, but not the same antib...
ORGANISM(S): Homo Sapiens 
PXD044426 | panorama
UnknownDiscovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies.
Not available
S-EPMC5458547 | biostudies-literature
UnknownRelationship Between Severity of Ischemia and Coronary Artery Disease for Different Stress Test Modalities in the ISCHEMIA Trial.
Not available
S-EPMC11658795 | biostudies-literature
UnknownChromatin activation as a unifying principle underlying pathogenic mechanisms in multiple myeloma.
Not available
S-EPMC7545147 | biostudies-literature
UnknownWhole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers.
Not available
S-EPMC4381520 | biostudies-literature
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