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ProteomicsTma108, a putative M1 aminopeptidase, defines specialized ribosomes in Saccharomyces cerevisiae
Ribosome specialization is an emerging concept which challenges the common assumption that translation relies on a standardized molecular machinery. In this work, we demonstrate that Tma108, a yeast uncharacterized translation machinery-associated factor, defines a subpopulation of the cellular ribo...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2016-09-27 | PXD003174 | Pride
Ribosomes Affinity purification (ap-ms) Yeast s. cerevisiae 
ProteomicsFunctional mapping of N-terminal residues in the yeast proteome uncovers novel determinants for mitochondrial protein import
N-terminal ends of polypeptides are critical for the selective co-translational recruitment of N-terminal modification enzymes. However, it is unknown whether specific N-terminal signatures differentially regulate protein fate according to their cellular functions. In this work, we developed an in-s...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-07-28 | PXD034922 | Pride
N-terminal acetyltransferases Immunoprecipitation Natc Natb S. cerevisiae Nata Selective translating ribosomes Affinity purification 
TranscriptomicsCharacterization of yap7 in Saccharomyces cerevisiae and the human pathogen Candida glabrata
This study aimed at characterizing the targets of the bZIP transcription factor Yap7 in two yeast species: Saccharomyces cerevisiae and the human pathogen Candida glabrata. Transcriptome analyses were thus conducted in wild type and yap7 knock out strains using Agilent microarrays.
ORGANISM(S): Saccharomyces cerevisiae 
2014-10-01 | E-MTAB-2653 | biostudies-arrayexpress
TranscriptomicsLooking for mitochondrial associated RNA
We investigated the peripheral mitochondrial localization of nuclear-encoded mRNAs (MLR) in various conditions in which translation was inhibited or the mRNA binding protein context altered (Delta puf3). We used cell fractionation protocols together with microarray to assess the distribution of mRNA...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-01 | E-GEOD-9393 | biostudies-arrayexpress
TranscriptomicsTranscriptome analyses of dhh1 mutants in yeast
Previous experiments revealed that DHH1, a RNA helicase involved in the regulation of mRNA stability and translation, complemented the phenotype of a Saccharomyces cerevisiae mutant affected in the expression of genes coding for monocarboxylic-acids transporters, JEN1 and ADY2. In wild type cells, J...
ORGANISM(S): Saccharomyces cerevisiae 
2014-09-08 | E-GEOD-60983 | biostudies-arrayexpress
UnknownSotrovimab therapy elicits antiviral activities against Omicron BQ.1.1 and XBB.1.5 in sera of immunocompromised patients.
Not available
S-EPMC11232389 | biostudies-literature
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