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MetabolomicsHif1α-Dependent Uncoupling Of Glycolysis Suppresses Tumor Cell Proliferation
Hypoxia-inducible factor-1α (HIF1α) attenuates mitochondrial activity while promoting glycolysis. Paradoxically, it remains unknown why lower glycolysis is compromised in human clear cell renal cell carcinomas (ccRCC), in which HIF1α acts a tumor suppressor by inhibiting cell autonomous proliferatio...
2024-03-15 | MTBLS8901 | MetaboLights
UnknownPutative porin of Bradyrhizobium sp. (Lupinus) bacteroids induced by glyphosate.
Not available
S-EPMC1950976 | biostudies-literature
TranscriptomicsIn vivo disruption of Rb-E2F-Ezh2 signaling loop causes bladder cancer development
Bladder cancer (BC) is a highly prevalent human disease in which Rb pathway inactivation and epigenetic alterations are common events. However, the connection between these two processes is still poorly understood. Here we show that the in vivo inactivation of all Rb family genes in the mouse urothe...
ORGANISM(S): Homo sapiens 
2014-10-02 | E-GEOD-38264 | biostudies-arrayexpress
UnknownA novel atypical hemolytic uremic syndrome-associated hybrid CFHR1/CFH gene encoding a fusion protein that antagonizes factor H-dependent complement regulation.
Not available
S-EPMC4279739 | biostudies-literature
UnknownInitiating Electron Transfer in Doubly Curved Nanographene Upon Supramolecular Complexation of C60.
Not available
S-EPMC9303211 | biostudies-literature
UnknownImpact of IPDE-SQ personality disorders on the healthcare and societal costs of fibromyalgia patients: a cross-sectional study.
Not available
S-EPMC4888611 | biostudies-literature
UnknownInnovative Approach to Early Lung Cancer Detection: Integrating a Comprehensive Screening Program and an Incidental Pulmonary Nodule Clinic.
Not available
S-EPMC12796536 | biostudies-literature
UnknownIdentification of a Dexamethasone Mediated Radioprotection Mechanism Reveals New Therapeutic Vulnerabilities in Glioblastoma.
Not available
S-EPMC7836009 | biostudies-literature
UnknownImpact of time to intubation on mortality and pulmonary sequelae in critically ill patients with COVID-19: a prospective cohort study.
Not available
S-EPMC8744383 | biostudies-literature
UnknownVoice Assistants as Consultants for Male Patients with Sexual Dysfunction: A Reliable Option?
Not available
S-EPMC9914936 | biostudies-literature
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