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ProteomicsProteomic landscape of atypical antipsychotics clinical response in blood plasma from schizophrenia patients
Antipsychotics are the main line of treatment for schizophrenia, despite being effective only in about 50% of patients. Additionally, serious side effects may cause medication drop-out, aggravated by a lack of understanding about how these drugs act at molecular level. As proteomics is a suitable...
ORGANISM(S): Homo sapiens (Human) 
2020-06-01 | PXD015049 | Pride
Proteomics Blood plasma Mass spectrometry Olanzapine Risperidone Schizophrenia Antipsychotics 
ProteomicsA snapshot of blood plasma proteomics in clinical response to atypical antipsychotics in schizophrenia – An exploratory study
Antipsychotics are usually the first option to treat schizophrenia; however, for a considerable fraction of patients, it lacks efficacy. Furthermore, there are no known biomarkers to indicate a treatment’s efficacy in a patient. Schizophrenia causes a large socioeconomic burden on countries along wi...
ORGANISM(S): Homo sapiens (Human) 
2020-06-01 | PXD015213 | Pride
Proteomics Blood plasma Mass spectrometry Schizophrenia Antipsychotics Risperidone Olanzapine. 
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