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TranscriptomicsDetection of Bacillus anthracis DNA in complex soil and air samples using next-generation sequencing [NimbleGen Array data]
One of the cornerstones of an effective biodefense strategy is the ability to detect infectious agents with a high degree of sensitivity and specificity in the context of a complex sample background. The nature of the B. anthracis genome, however, renders specific detection difficult, due to close ...
ORGANISM(S): Bacillus anthracis str. Ames 
2013-06-27 | E-GEOD-48316 | biostudies-arrayexpress
UnknownDevelopment of ALL-Hematotox: predicting post-CAR T-cell hematotoxicity in B-cell acute lymphoblastic leukemia.
Not available
S-EPMC11923441 | biostudies-literature
TranscriptomicsGene expression profile of isolated splenic NK cells from mice treated with ptaquiloside and/or selenium
To better understand the immunosuppressor mechanism of ptaquiloside in splenic NK cells and the reversion of this effect by selenium, we have employed whole genome microarray expression profile to identify genes associated with immunosuppression. Among 89 genes induced by ptaquiloside treatment in s...
ORGANISM(S): Mus musculus 
2013-07-24 | E-GEOD-30629 | biostudies-arrayexpress
ProteomicsAffinity proteomics on PEX1 and PEX1-G843D in HCT116 Cells
The PEX1/PEX6 AAA-ATPase is required for the biogenesis and maintenance of peroxisomes. Mutations in HsPEX1 and HsPEX6 disrupt peroxisomal matrix protein import and are the leading cause of Peroxisome Biogenesis Disorders (PBDs). The most common disease-causing mutation in PEX1 is the HsPEX1G843D al...
ORGANISM(S): Homo sapiens (Human) 
2025-04-28 | PXD061295 | Pride
Human Flag-affinity Hct116 Pex1 
UnknownIL12 Abrogates Calcineurin-Dependent Immune Evasion during Leukemia Progression.
Not available
S-EPMC6889000 | biostudies-literature
TranscriptomicsThe C. elegans SNAP complex component SNPC-4 coats piRNA domains and globally affects piRNA abundance
Remarkably, tens of thousands of piwi-interacting RNAs (piRNAs) arise from a minimal number of discrete clustered regions in many organisms. However, it remains unclear if organization into these domains contributes to the highly coordinated, germline-specific expression of these small RNAs. Here, w...
ORGANISM(S): Caenorhabditis elegans 
2014-11-17 | E-GEOD-53412 | biostudies-arrayexpress
TranscriptomicsThe Microbial Detection Array for Detection of Emerging Viruses in Clinical Samples - A Useful Panmicrobial Diagnostic Tool
Emerging viruses are usually endemic to tropical and sub-tropical regions of the world, but increased global travelling, climate changes and changes in lifestyle are believed to contribute to the spread of these viruses into new regions. For many of them, the disease symptoms are similar to each oth...
ORGANISM(S): Toscana virus 
2013-11-15 | E-GEOD-52324 | biostudies-arrayexpress
TranscriptomicsThe Microbial Detection Array for Detection of Emerging Viruses in Clinical Samples - A Useful Panmicrobial Diagnostic Tool--Array Version 2f
Emerging viruses are usually endemic to tropical and sub-tropical regions of the world, but increased global travelling, climate changes and changes in lifestyle are believed to contribute to the spread of these viruses into new regions. For many of them, the disease symptoms are similar to each oth...
ORGANISM(S): Dengue virus 1 
2014-03-05 | E-GEOD-55576 | biostudies-arrayexpress
GenomicsDerivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations
The presence of two active X chromosomes (XaXa) is a hallmark of the ground state of pluripotency specific to murine embryonic stem cells (ESCs). Human ESCs invariably exhibit signs of X chromosome inactivation (XCI) and are considered developmentally more advanced than their murine counterparts. W...
ORGANISM(S): Homo sapiens 
2010-05-28 | E-GEOD-21141 | biostudies-arrayexpress
TranscriptomicsMicroarray gene expression profiles from temperature acclimated atrial, ventricular compact and spongy tissues of Pacific bluefin tuna Thunnus orientalis
In this study, we examined the transcriptomic responses to temperature acclimation (14oC, 20oC, and 25oC) in atrial and ventricular tissues of Pacific bluefin tuna (PBFT). A global gene expression analysis using a bluefin tuna-specific microarray indicated profound changes in expression of genes ass...
ORGANISM(S): Thunnus orientalis 
2012-03-31 | E-GEOD-36886 | biostudies-arrayexpress
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