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ProteomicsA mass spectrometry-based approach for the identification of Kpnβ1 binding partners in cancer cells
Karyopherin beta 1 (Kpnβ1) is the principal nuclear importer of cargo proteins and plays a role in many cellular processes. Its expression is upregulated in cancer and essential for cancer cell viability, thus the identification of its binding partners might help in the discovery of anti-cancer ther...
ORGANISM(S): Homo sapiens (Human) 
2022-11-03 | PXD034805 | Pride
Cancer Kpnb1 
ProteomicsProteogenomic analysis of Mycobacterium smegmatis using high resolution mass spectrometry
Biochemical evidence is vital for accurate genome annotation. The integration of experimental data collected at the proteome level using high resolution mass spectrometry allows for improvements in genome annotation by providing evidence for novel gene models, while validating or modifying others. ...
ORGANISM(S): Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) 
2016-03-31 | PXD003500 | Pride
Mass spectrometry Genome annotation Mycobacterium smegmatis Proteogenomics Proteomics 
ProteomicsProteomic Time-Course Investigation into the Effects of Exposure of Mycobacterium smegmatis to Sub-Lethal Dose of Rifampicin
Drug susceptible Mycobacterium smegmatis (Mc2-155) was exposed to a sub-MIC concentration of antimycobacterial drug Rifampicin (treated) or DMSO (control). Cells were harvested at 30, 255 and 300 minutes post-exposure and the proteome at each time analysed using LC-MS/MS on a Thermo Q-Exactive.
ORGANISM(S): Mycobacterium Smegmatis Str. Mc2 155 (ncbitaxon:246196) 
2019-03-18 | MSV000083589 | MassIVE
ProteomicsQuantitative proteomic analysis of HIV-1 Tat-induced dysregulation in SH-SY5Y neuroblastoma cells
Despite affecting up to 70% of HIV+ patients and being the leading cause of dementia in patients under 40 years, the molecular mechanisms involved in the onset of HAND are not well understood. To address this, we performed SILAC-based quantitative proteomic analysis on HIV-Tat treated SH-SY5Y neurob...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-03-18 | MSV000083590 | MassIVE
ProteomicsMsmegmatis strMC2 155 - Whole organism, iBAQ (Potgieteretal,frontmicrobiol2016)
abundance based on iBAQ, Interaction consistency score: 11.4, Coverage: 45
ORGANISM(S): 246196 
2016-00-00 | 1196164352 | PAXDB
ProteomicsMsmegmatis strMC2 155 - Whole organism, iBAQ (Potgieteretal,frontmicrobiol2016)
abundance based on iBAQ, Interaction consistency score: 12.3, Coverage: 45
ORGANISM(S): 246196 
2016-00-00 | 2359555123 | PAXDB
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