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ProteomicsEvaluation of serum supplementation on the development of Haemonchus contortus larvae in vitro and on compound screening results
A high-throughput platform for assessing the activity of synthetic or natural com-pounds on the motility and development of Haemonchus contortus larvae has been estab-lished for identifying new anthelmintic compounds active against strongylid nema-todes. This study evaluated the impact of serum supp...
ORGANISM(S): Haemonchus contortus (Barber pole worm) 
2025-02-27 | PXD060092 | Pride
Haemonchus contortus  parasitic nematode  in vitro culture  serum supplementation  an-thelmintic screening 
ProteomicsProteomic analysis of dafachronic acid-associated alterations in Haemonchus contortus
To investigate the molecular changes (protein level) associated with dafachronic acid and the nuclear hormone receptor DAF-12 in Haemonchus contortus following exsheathment of the thrid-stage larvae, protein was extracted from replicates (n = 4), processed and analysed using LC-MS/MS.
ORGANISM(S): Haemonchus contortus (Barber pole worm) 
2019-11-13 | PXD012878 | Pride
Dafachronic acid  dauer  development  haemonchus contortus 
ProteomicsProteome of Anoplocephala perfoliata elucidate lineage-specific features of a “neglected” equine tapeworm
Anoplocephala perfoliata is the most prevalent and pathogenic tapeworm (cestode) of horses worldwide, yet it remains molecularly understudied. Here, we present a chromosome-scale nuclear genome and matched proteomes for this parasite, establishing the first high-resolution molecular resource for the...
ORGANISM(S): Anoplocephala perfoliata 
2025-12-15 | PXD067162 | Pride
Anoplocephalidae Anoplocephala perfoliata Lc-ms/ms 
ProteomicsThe developmental phosphoproteome of Haemonchus contortus
Protein phosphorylation plays essential roles in the biology of cellular processes. Despite recent progress in the genomics, transcriptomics and proteomics of a range of socioeconomically important parasitic nematodes, there is scant phosphoproteomic data to underpin fundamental molecular biological...
ORGANISM(S): Haemonchus contortus (Barber pole worm) 
2019-12-20 | PXD015099 | Pride
Lc-ms/ms Dia Parasitic nematode Haemonchus contortus Phosphoproteome 
ProteomicsHaemonchus contortus secretome LC-MS/MS
The excretory-secretory (ES) proteins are the molecules that actively or passively released by parasite at the parasite-host interface to maintain a physiological and immunological relationship with the host. In the present study, we characterised the excretory-secretory products from the short-term...
ORGANISM(S): Haemonchus contortus (Barber pole worm) 
2019-06-18 | PXD012503 | Pride
Haemonchus contortus Lc-ms/ms Parasitic nematode Secretome 
ProteomicsThe proteome of extracellular vesicles from Haemonchus contortus
Parasitic worms have a major global impact in human and animal populations due to the chronicity of their infections. These parasites have an exquisite capacity to survive in host animals. There is a growing body of evidence that extracellular vesicles (EVs) are intimately involved in parasitism, an...
ORGANISM(S): Haemonchus contortus (Barber pole worm) 
2023-08-07 | PXD041918 | Pride
Haemonchus contortus Proteomics Lc-ms/ms 
ProteomicsSarcoptes scabiei somatic proteomes
Presently, there is a dearth of proteomic data for parasitic mites and their relationship with the host animals. Here, using a high throughput LC-MS/MS-based approach, we undertook the first comprehensive, large-scale proteomic investigation of egg and adult female stages of the scabies mite, Sarcop...
ORGANISM(S): Sarcoptes scabiei 
2022-11-11 | PXD032148 | Pride
Proteomes  sarcoptes scabiei  parasitic mite  egg and adult stages  scabies  human 
ProteomicsLFQ of compund treated Haemonchus contortus
This study applied the LFQ proteome to infer molecular targets and protein–ligand interactions of candidate nematocidal compounds in Haemonchus contortus. Protein extracts were prepared under standardised conditions, and then processed for quantitative proteomics using high-resolution LC-MS/MS. Resu...
ORGANISM(S): Haemonchus contortus (Barber pole worm) 
2026-07-19 | PXD075211 | Pride
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