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MetabolomicsOrnithine Decarboxylase in Gastric Epithelial Cells Promotes the Immunopathogenesis of Helicobacter pylori Infection

Colonization by H. pylori is associated with a wide range of gastric diseases, ranging from superficial gastritis to more severe pathologies, including intestinal metaplasia and adenocarcinoma. The interplay of the host response and the pathogen affect the outcome of disease. One major component ...

2022-06-15 | MTBLS3235 | MetaboLights
MetabolomicsMetabolite comparison of mouse gastric tissue and glands
Not available
ORGANISM(S): Mus musculus 
ST000354 | MetabolomicsWorkbench
MetabolomicsMetabolic biomarkers of gastric cancer

Plasma samples were analyzed using UPLC-MS/MS untargeted metabolomics. The dataset comprised 144 participants. Partial least squares discriminant analysis (PLS-DA) three-dimensional scores plot distinguishing GC patients from non-GC controls. Metabolic profiling and differential comparison identi...

2026-09-29 | MTBLS12684 | MetaboLights
TranscriptomicsGastric Cancer Subtyping (Australian Patient Cohort)
Genome-wide mRNA expression profiles of 70 primary gastric tumors from the Australian patient cohort. Like many cancers, gastric adenocarcinomas (gastric cancers) show considerable heterogeneity between patients. Thus, there is intense interest in using gene expression profiles to discover subtypes ...
ORGANISM(S): Homo sapiens 
2012-07-04 | E-GEOD-35809 | biostudies-arrayexpress
MetabolomicsGut microbiota carcinogen metabolism causes distal tissue tumours

Exposure to environmental pollutants and human microbiome composition are important predisposition factors for tumour development. Similar to drug molecules, pollutants are typically metabolised in the body, which can change their carcinogenic potential and impact tissue distribution through alte...

2024-06-05 | MTBLS3581 | MetaboLights
TranscriptomicsGenetic Landscape of Copy Number Alterations in Gastric Cancer
Genome-wide DNA copy number profiling of gastric tumors and matched non-maligant samples. The affymetrix SNP6 array was used to obtain DNA copy number profiles in 193 gastric tumors and 98 matched gastric non-malignant samples. Genomic DNA extracted from 193 gastric tumors and 98 matched gastric non...
ORGANISM(S): Homo sapiens 
2012-02-10 | E-GEOD-31168 | biostudies-arrayexpress
ProteomicsGastric ulcer mice gastric tissue
Indomethacin was applied to establish a mice model of gastric ulcer, 24 h later, gastric tissue were obtain
ORGANISM(S): Mus musculus (Mouse) 
2025-05-07 | PXD058482 | Pride
Mice Gastric tissue Gastric ulcer 
GenomicsNanoscale Chromatin Profiling of Gastric Adenocarcinoma
To identify chromatin alterations in primary gastric adenocarcionomas, we performed nano-scale chromatin immunoprecipitation-sequencing (Nano-CHiPseq) of histone modifications in 5 gastric cancers and matched normal tissues, We identified hundreds of somatically-altered promoters (marked by H3K4me3)...
ORGANISM(S): Homo sapiens 
2014-07-30 | E-GEOD-51776 | biostudies-arrayexpress
TranscriptomicsmiRNA profiling by array of human paired adipose tissue (subcutaneous and omentum) before and after gastric-bypass and weight loss
Objective: Adipose tissue plays a key role in obesity related metabolic dysfunction. MicroRNA (miRNA) are gene regulatory molecules involved in inter-cellular and inter-organ communication. We hypothesised that miRNA levels in adipose tissue would change after gastric bypass surgery and that this wo...
ORGANISM(S): Homo sapiens 
2019-12-16 | E-MTAB-8594 | biostudies-arrayexpress
TranscriptomicsExpression profiles of microRNAs in gastric cancer
We analyzed expression profiles of microRNAs from 22 paired gastric cancer and normal tissues and identified differentially expressed microRNAs. RNA from paired normal and tumor specimens in 22 gastric cancer patients were extracted and treated for microRNA microarray analysis.
ORGANISM(S): Homo sapiens 
2011-04-21 | E-GEOD-28700 | biostudies-arrayexpress
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