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ProteomicsMudPIT analysis of the Dbf4/Chiffon and Gcn5 complex in Drosophila
During evolution, there has been an expansion in the diversity of histone acetyltransferase Gcn5-containing complexes. All Gcn5 complexes share Sgf29 and Ada3 subunits, which together with their respective Ada2 homolog, enable nucleosomal HAT activity. In metazoans, including Drosophila, there are t...
ORGANISM(S): Drosophila Melanogaster (ncbitaxon:7227) 
2017-12-07 | MSV000081791 | MassIVE
ProteomicsGcn5 and Esa1 function as histone crotonyltransferases to regulate crotonylation-dependent transcription
Histone post-translational modifications (PTMs) are critical for processes such as transcription. The more notable among these are the non-acetyl histone lysine acylation modifications such as crotonylation, butyrylation and succinylation. However, the biological relevance of these PTMs is not fully...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) Xenopus laevis (African clawed frog) 
2019-11-06 | PXD015488 | Pride
Gcn5-ada2-ada3 (ada) complex Histone modification Crotonylation Gene transcription Epigenetics Esa1- yng2-epl1 (piccolo nua4) complex 
UnknownAda2 and Ada3 Regulate Hyphal Growth, Asexual Development, and Pathogenicity in Beauveria bassiana by Maintaining Gcn5 Acetyltransferase Activity.
Not available
S-EPMC10269768 | biostudies-literature
ProteomicsMudPIT analyses of the proteins co-purified with Ada2b-PB-FLAG-HA FLAG-affinity purified from Drosophila melanogaster S2 cells
Protein Complexes Purification- Stable S2 cell lines expressing Ada2b (isoform B; NP_001027151.1) in the pRmHa3-CHA2FL2 (Ada2b-PBH2F2) were maintained at 1-2 e6 cells/mL in SFX medium (HyQ SFX-Insect). Cells stably transfected with empty vector served as negative controls. Protein complexes containi...
ORGANISM(S): Drosophila Melanogaster (ncbitaxon:7227) 
2018-11-20 | MSV000083153 | MassIVE
UnknownThe SAGA HAT module is tethered by its SWIRM domain and modulates activity of the SAGA DUB module.
Not available
S-EPMC10226619 | biostudies-literature
TranscriptomicsTranscription profiling by array of Drosophila dAda2a amd dAda3 mutants at the puparium formation stage
Analyze the Drosophila ATAC complex function at the puparium formation stage. dAda2a and dAda3 were used.
ORGANISM(S): Drosophila melanogaster 
2010-06-24 | E-MEXP-2765 | biostudies-arrayexpress
UnknownTwo Drosophila Ada2 homologues function in different multiprotein complexes.
Not available
S-EPMC153191 | biostudies-literature
UnknownHost cell factor and an uncharacterized SANT domain protein are stable components of ATAC, a novel dAda2A/dGcn5-containing histone acetyltransferase complex in Drosophila.
Not available
S-EPMC1347012 | biostudies-literature
UnknownHuman ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein.
Not available
S-EPMC2590711 | biostudies-literature
TranscriptomicsAda2b isoforms
Gene expression profiling of the two ADA2b protein (ADA2bS and ADA2bL) in Drosophila melanogaster
ORGANISM(S): Drosophila melanogaster 
2012-09-30 | E-MEXP-3747 | biostudies-arrayexpress
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