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ProteomicsNuclear PTEN safeguards pre-mRNA splicing to link Golgi apparatus for its tumor suppressive role
Dysregulation of pre-mRNA alternative splicing (AS) is closely associated with cancers. However, the relationships between the AS and classic oncogenes/tumor suppressors are largely unknown. Here we show that the deletion of tumor suppressor PTEN alters pre-mRNA splicing in its phosphatase-independe...
ORGANISM(S): Homo sapiens (Human) 
2018-10-18 | PXD009681 | Pride
U2af2 Golgi Tumor suppressor Spliceosome Pten Golga2 Protein-protein interaction Alternative splicing 
ProteomicsDissection of Blood Ecosystem in SARS-CoV-2 Omicron Patients
Here, we systematically profiled clinical phenomes, transcriptomes, proteomes, metabolomes, and immune repertoire of blood cells or plasma in over 1000 specimens from SARS-CoV-2 Omicron patients across multiple disease phases.
ORGANISM(S): Homo Sapiens 
2024-08-02 | PXD045174 |
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