Sort   by:  
 Page size 
UnknownIdeal Photothermal Materials Based on Ge Subwavelength Structure.
Not available
S-EPMC11547708 | biostudies-literature
ProteomicsInferior Temporal Gyrus in Human Ageing: a Quantitative Protein Profiling Work based on Chinese Human Brain Bank
The temporal lobe is the cerebral cortex with critical function. The superior and middle gyrus of temporal lobe have been well studied, however, present perceptions on inferior temporal gyrus remains limited. The understanding of age-related protein profile change in human inferior temporal gyrus ha...
ORGANISM(S): Homo sapiens (Human) 
2015-12-07 | PXD002528 | Pride
Inferior temporal gyrus  tmt  proteomics  ageing  chinese human brain bank. 
ProteomicsProtein Profile Changes in the Frontotemporal Lobes in Human Severe Traumatic Brain Injury
Severe traumatic brain injury (sTBI) is a serious public health issue with high morbidity and mortality rates. Previous proteomic studies on sTBI have mainly focused on human cerebrospinal fluid and serum, as well as on brain protein changes in murine models. However, human proteomic data in sTBI br...
ORGANISM(S): Homo sapiens (Human) 
2016-04-15 | PXD002783 | Pride
Severe traumatic brain injury  tmt (tandem mass tags)  human  proteomics 
ProteomicsProteomic profiling of sclerosis hippocampus revealed dysregulated packaging of vesicular neurotransmitters in temporal lobe epilepsy
Proteomics and bioinformatic analyses of hippocampus were performed. High-resolution liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS), in combination with TMT-6plex quantification, was applied for global protein expression analysis. The proteomics results were validated by Wester...
ORGANISM(S): Homo sapiens (Human) 
2020-07-17 | PXD010544 | Pride
Temporal lobe epilepsy Proteomics Vesicle transmitters packaging Hippocampus sclerosis Annexin 
ProteomicsProteomic profiling of sclerosis hippocampus revealed dysregulated packaging of vesicular neurotransmitters in temporal lobe epilepsy
Proteomics and bioinformatic analyses of hippocampus were performed. High-resolution liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS), in combination with TMT-6plex quantification, was applied for global protein expression analysis. The proteomics results were validated by Wester...
ORGANISM(S): Homo sapiens (Human) 
2020-07-17 | PXD010543 | Pride
Temporal lobe epilepsy Proteomics Vesicle transmitters packaging Hippocampus sclerosis Annexin 
ProteomicsALKBH7, a mitochondrial member of AlkB family, binds histones in vitro, part 1
Human genome encodes 9 AlkB family members, one of which is ALKBH7. In this study, we found recombinant ALKBH7 could bind bulk histones in GST pull-down and attenuate the signal of H4K20me2 in demethylation assays. With mass spectrometry, we also identified several potential ALKBH7-interacting prote...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD008318 | Pride
Alkbh7 mitochondrion histones 
ProteomicsALKBH7, a mitochondrial member of AlkB family, binds histones in vitro, part 2
Human genome encodes 9 AlkB family members, one of which is ALKBH7. In this study, we found recombinant ALKBH7 could bind bulk histones in GST pull-down and attenuate the signal of H4K20me2 in demethylation assays. With mass spectrometry, we also identified several potential ALKBH7-interacting prote...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD008319 | Pride
Alkbh7 mitochondrion histone 
ProteomicsQuantitative proteomic characterization of senile plaques from Alzheimer's disease and non-demented brain
The deposition of amyloid senile plaques (SPs) play a central role in Alzheimer’s disease (AD), but the mechanisms by which SPs induce neural toxicity are disputed. Genetically engineered mouse models emphasising SPs have had limited success in reproducing the neuropathology of AD, and have also fai...
ORGANISM(S): Homo sapiens (Human) 
2019-02-18 | PXD005824 | Pride
Human Brain Alzheimer's disease Amyloid plaque Senile plaque 
ProteomicsQuantitative proteomic characterization of hippocampus during ageing from APP/PS1 mice brain
Ageing is the most important non-genetic risk factor of late-onset AD. However, the relationship between AD and aging process is still unclear. Here, by comparative analysis, we demonstrated the low correlation between AD and aging process during ageing.
ORGANISM(S): Mus musculus (Mouse) 
2022-03-20 | PXD005875 | Pride
Mouse Brain Hippocampus Alzheimer's disease 
ProteomicsQuantitative proteomic characterization of temporal lobe during ageing from APP/PS1 mice brain
Ageing is the most important non-genetic risk factor of late-onset AD. However, the relationship between AD and aging process is still unclear. Here, by comparative analysis, we demonstrated the low correlation between AD and aging process during ageing.
ORGANISM(S): Mus musculus (Mouse) 
2022-04-07 | PXD005877 | Pride
Mouse Brain Alzheimer's disease Temporal lobe 
Sort   by:  
 Page size