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GenomicsSystematic study of mammalian RhoGAPs and GEFs
Systematic study of mammalian RhoGAPs and GEFs and their role in regulating Rho signalling
PRJEB27183 | ENA
GenomicsSystematic evaluation of GAPs and GEFs identifies ARHGAP45 as a targetable leukemia-specific RhoGAP dependency
Systematic evaluation of GAPs and GEFs identifies ARHGAP45 as a targetable leukemia-specific RhoGAP dependency
PRJNA1140357 | ENA
TranscriptomicsSystematic evaluation of GAPs and GEFs identifies ARHGAP45 as a targetable leukemia-specific RhoGAP dependency
GTPase-activating proteins (GAPs) and guanine nucleotide exchange factors (GEFs) function as negative and positive regulators of small GTPases, respectively, and play key roles in cell fate determination. The aberrant function of GAPs and GEFs has long been implicated in cancer development but their...
ORGANISM(S): Homo sapiens 
2024-07-26 | GSE273164 | GEO
UnknownRab GEFs and GAPs.
Not available
S-EPMC2929657 | biostudies-literature
UnknownMimicking GEFs: a common theme for bacterial pathogens.
Not available
S-EPMC3332549 | biostudies-literature
UnknownAdvancing early warning capabilities with CHIRPS-compatible NCEP GEFS precipitation forecasts.
Not available
S-EPMC9246965 | biostudies-literature
UnknownRho GAPs and GEFs: controling switches in endothelial cell adhesion.
Not available
S-EPMC4049857 | biostudies-literature
UnknownMechanism of the promotion of GEFS+ by the STAT3-mediated expression of interleukin-6.
Not available
S-EPMC9561518 | biostudies-literature
UnknownRegulation and function of P-Rex family Rac-GEFs.
Not available
S-EPMC4601503 | biostudies-literature
UnknownPhosphatidic acid-dependent localization and basal de-phosphorylation of RA-GEFs regulate lymphocyte trafficking.
Not available
S-EPMC7325102 | biostudies-literature
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