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MetabolomicsMetabolic signatures of Arabidopsis thaliana abiotic stress responses elucidate patterns in stress priming, acclimation, and recovery

Temperature, water and light are 3 abiotic stress factors that have major influences on plant growth, development and reproduction. Plants can be primed by a prior mild stress to enhance their resistance to future stress. We used an untargeted metabolomics approach to examine Arabidopsis thal...

2022-05-30 | MTBLS3672 | MetaboLights
ProteomicsDifferential view on the bile acids stress response of Clostridioides difficile_longterm stress
In this study, we aimed at the characterization of C. difficile’s stress response to the main four human bile acids. Although, a phenotypically description of growth differences upon challenge with different bile acids has been described (Lewis 2016, Thanissery 2017), there is no information on the ...
ORGANISM(S): Peptoclostridium difficile (strain 630) (Clostridium difficile) 
2019-02-09 | PXD010525 | Pride
General and specific stress response Proteomics Motility Clostridioides difficile Bile acids Differential analysis Flagella 
MetabolomicsSnail reprograms glucose metabolism by repressing PFKP allowing cancer cell survival under metabolic stress
Dynamic regulation of glucose flux between aerobic glycolysis and the pentose phosphate pathway (PPP) during epithelial-mesenchymal transition (EMT) is not well-understood. Here we show that Snail (SNAI1), a key transcriptional repressor of EMT, regulates glucose flux toward PPP, allowing cancer cel...
2017-11-07 | MTBLS387 | MetaboLights
TranscriptomicsThe rsa1-1 mutation affects global gene expression in Arabidopsis thaliana with or without salt stress
Salt stress is one of the most severe environmental conditions which cause huge losses in crop production worldwide. We identified a novel calcium-binding protein and used the Affymetrix whole-genome arrays to define downstream targets of this important protein. We used the microarrays to reveal the...
ORGANISM(S): Arabidopsis thaliana 
2013-07-07 | E-GEOD-39236 | biostudies-arrayexpress
TranscriptomicsLocation-specific responses to thermal stress in larvae of the reef-building coral Montastraea faveolata
The potential to adapt to a changing climate depends in part upon the standing genetic variation present in wild populations. In corals, the dispersive larval phase is particularly vulnerable to the effects of environmental stress. Larval survival and response to stress during dispersal and settleme...
ORGANISM(S): Montastraea faveolata 
2010-06-23 | E-GEOD-19998 | biostudies-arrayexpress
TranscriptomicsLight activation of the sigmaB-mediated general stress-response of Bacillus subtilis
The sigma(B)-dependent general stress response in the common soil bacterium Bacillus subtilis can be elicited by a range of stress factors, such as starvation or an ethanol-, salt-, or heat-shock, via a complex upstream signaling cascade. Additionally, sigma(B) can be activated by blue light, via th...
ORGANISM(S): Bacillus subtilis 
2010-05-16 | E-GEOD-19464 | biostudies-arrayexpress
TranscriptomicsHalobacterium NRC-1 General transcription factor perturbation
Halobacterium cells, specified general transcription factor knock-out strains or plasmid expressed 6-His tagged general transcription factor strains, were grown to mid-log phase. RNA extractions were performed using the Stratagene Absolutely RNA Miniprep Kit and RNA quality checked with the Agilent...
ORGANISM(S): Halobacterium sp. NRC-1 
2010-05-27 | E-GEOD-7713 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae response to nitrosative stress
Nitric oxide and NO-derived species (RNS) are defense molecules with broad antimicrobial activity. Micro-organisms have developed strategies to sense RNS and counteract their damaging effects. We used Saccharomyces cerevisiae, harbouring a deletion of YHB1 that encodes the main NO scavenger enzyme, ...
ORGANISM(S): Saccharomyces cerevisiae 
2006-03-02 | E-MEXP-580 | biostudies-arrayexpress
ProteomicsDifferential view on the bile acids stress response of Clostridioides difficile
In this study, we aimed at the characterization of C. difficile’s stress response to the main four human bile acids. Although, a phenotypically description of growth differences upon challenge with different bile acids has been described (Lewis 2016, Thanissery 2017), there is no information on the ...
ORGANISM(S): Peptoclostridium difficile (strain 630) (Clostridium difficile) 
2019-02-12 | PXD010514 | Pride
General and specific stress response Proteomics Motility Clostridioides difficile Bile acids Differential analysis Flagella 
TranscriptomicsTranscription profiling of Arabopsis response to Stress Treatments AtGenExpress
AtGenExpress: A multinational coordinated effort to uncover the transcriptome of the multicellular model organism Arabidopsis thaliana; The activity of genes and their encoded products can be regulated in several ways, but transcription is the primary level, since all other modes of regulation (RNA ...
ORGANISM(S): Arabidopsis thaliana 
2008-06-13 | E-GEOD-5623 | biostudies-arrayexpress
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