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TranscriptomicsTranscriptional Profile Analysis of RPGRORF15 frameshift mutation
Purpose: To identify genes and molecular mechanisms associated with disease progression during (7 weeks of age) and after (16 weeks) the peak of photoreceptor death in dogs affected with XLPRA2, a canine model of early-onset XLRP caused by a microdeletion in RPGR exon ORF15. Methods: Expression prof...
ORGANISM(S): Canis lupus familiaris 
2010-10-22 | E-GEOD-19124 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of pig alveolar macrophages infected with Porcine Respiratory Reproductive Syndrome Virus
A primary culture of Porcine Alveolar Macrophages (PAM) from six animals was split in two: one was infected at a multiplicity of infection (MOI) of 10 with a 13th passage of PRRSV Lelystad virus. The other culture was maintained as control. The percentage of infected cells ranged between 60 and 70% ...
ORGANISM(S): Sus scrofa 
2008-07-01 | E-MEXP-1350 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of porcine alveolar macrophages (PAM) after antibody-mediated crosslinking of sialoadhesin (Sn, Siglec-1)
In the present study, Sn expressed on primary pig macrophages was crosslinked with the anti-Sn monoclonal antibody 41D3 and the mRNA expression profiles were compared, using the Affymetrix microarray technology, to macrophages incubated with the irrelevant, isotype matched, monoclonal antibody 13D12
ORGANISM(S): Sus scrofa 
2007-03-09 | E-MEXP-991 | biostudies-arrayexpress
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