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MetabolomicsTelomere-to-telomere genome of Stylosanthes guianensis uncovers symbiotic adaptation to phosphorus-deficient soils
Thirty-day-old Stylosanthes guianensis seedlings were subjected to two treatments: inoculation with Bradyrhizobium (Br) strain LZ3-2 and treatment without Br inoculation (Control). Following transplantation into acidic soil, root samples were harvested 60 days after transplanting, flash-frozen in li...
2026-05-21 | MTBLS14548 | MetaboLights
MetabolomicsCreation and Characterization of a Genomically Hybrid Strain in the Nitrogen-Fixing Symbiotic Bacterium Sinorhizobium meliloti
Many bacteria, often associated with eukaryotic hosts and of relevance for biotechnological applications, harbor a multipartite genome composed of more than one replicon. Biotechnologically relevant phenotypes are often encoded by genes residing on the secondary replicons. A synthetic biology approa...
2021-03-17 | MTBLS576 | MetaboLights
TranscriptomicsExpression data from peripheral blood mononuclear cell in patients with type 1 diabetes before and after peripheral stem cell transplantation
Autologous nonmyeloablative hematopoietic stem cell transplantation (AHST) was the first therapeutic approaches that can improve beta cell function in type 1 diabetic (T1D) patients. This study was designed to investigate the potential mechanisms involved.We applied AHST to nine T1D patients diagnos...
ORGANISM(S): Homo sapiens 
2012-02-20 | E-GEOD-29908 | biostudies-arrayexpress
TranscriptomicsGene expression following myocardial infarction with and without stem cell transplantation
Background: Bone marrow-derived multipotent progenitor cell (MPC) transplantation leads to short term functional and bioenergetic improvement in a porcine model of postinfarction Left Ventricular (LV) remodeling despite a low engraftment rate. However, the long term outcome after MPC transplantation...
ORGANISM(S): Sus scrofa 
2010-04-12 | E-GEOD-14643 | biostudies-arrayexpress
TranscriptomicsKidney transplantation
In this study, we examined transcriptional profiles from 3 different microarray platforms, across 103 peripheral blood samples with and without acute rejection, to find a critical gene-set for the diagnosis of acute renal rejection that matched biopsy diagnosis, irrespective of patient demographics,...
ORGANISM(S): Homo sapiens 
2012-12-26 | E-GEOD-14067 | biostudies-arrayexpress
GenomicsBLUEPRINT DNA methylation profiles of graft donors in allogenic hematopoietic stem cell transplantation
Allogenic hematopoietic stem cell transplantation (HSCT) is a curative treatment for many hematological conditions. Acute graft-versus-host disease (aGVHD) is a prevalent immune-mediated complication following HSCT. Current diagnostic biomarkers that correlate with aGVHD severity, progression, and t...
EGAS00001001287 | EGA
TranscriptomicsBIOMARGIN study: Gene expression profiling in patients with a kidney transplantation
Microarrays were used to analyze the gene expression in peripheral blood and kidney allograft biopsies from patients with a kidney transplantation to get more insight in the molecular mechanisms underlying the different clinical phenotypes of kidney transplant rejection. 117 peripheral blood samples...
ORGANISM(S): Homo sapiens 
2019-08-15 | E-GEOD-129166 | biostudies-arrayexpress
UnknownThe Impact of Genome-wide Histocompatibility on Liver Transplantation Outcomes.
Not available
S-EPMC12711261 | biostudies-literature
TranscriptomicsTranscription profiling of rat syngeneic (sTX) and allogeneic kidney (aTX) transplantation compared to control (ctr) kidneys
Microarray analyses provide a powerful approach to identify gene expression alterations following kidney transplantation. However, the heterogeneity of human kidney transplant specimens and the variation in sample preparation precludes conclusions regarding the underlying mechanisms of the observed ...
ORGANISM(S): Rattus norvegicus 
2008-06-14 | E-GEOD-6497 | biostudies-arrayexpress
TranscriptomicsKidney transplantation (SMD set)
In this study, we examined transcriptional profiles from 3 different microarray platforms, across 103 peripheral blood samples with and without acute rejection, to find a critical gene-set for the diagnosis of acute renal rejection that matched biopsy diagnosis, irrespective of patient demographics,...
ORGANISM(S): Homo sapiens 
2012-12-26 | E-GEOD-14357 | biostudies-arrayexpress
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