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TranscriptomicsExpression profiling in VCP-associated myopathy
Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia (IBMPFD) is caused by mutations in the Valosin Containing Protein (VCP) gene on chromosome 9p12-13. To elucidate affected signaling transduction axes in IBMPFD, we determined expression profiles using microarra...
ORGANISM(S): Homo sapiens 
2012-07-18 | E-GEOD-30806 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat adipose tissue - Diabetes biomarker disease progression study
The goals and objectives: To study Type 2 diabetes progression and the development of insulin resistance in two animal models with and without a high fat diet superimposed on these models. Background: Diabetes is a systemic metabolic imbalance involving multiple tissues/organs, and an early hallma...
ORGANISM(S): Rattus norvegicus 
2009-11-10 | E-GEOD-13268 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat strains GotoKakizake) rats and 51 liver sample from WKY (WistarKyoto) rats feeded with normal diet (ND) and high fat diet (HFD) and sacrificed at 5 different ages: 4, 8, 12, 16, and 20 weeks - diabetes biomarker disease progression study in rat liver
The goals and objectives: To study Type 2 diabetes progression and the development of insulin resistance in two animal models with and without a high fat diet superimposed on these models. Background: Diabetes is a systemic metabolic imbalance involving multiple tissues/organs, and an early hallma...
ORGANISM(S): Rattus norvegicus 
2009-11-10 | E-GEOD-13270 | biostudies-arrayexpress
TranscriptomicsExpression data from human PBMC induced by mixed Congeners of PCBs at Human equivalence
Exposure to Polychlorobiphenyls (PCBs) is known to cause serious health effects in human but the gene expression profiles leading to development of different diseases and disorders are not fully understood. The knowledge of global gene expression will help us to develop early disease or disorder bio...
ORGANISM(S): Homo sapiens 
2015-06-22 | E-GEOD-22668 | biostudies-arrayexpress
TranscriptomicsExpression data from 45 Month Slovak Children with high POPs exposure
Exposure to Persistant Organic Pollutants (POPs) is known to cause serious health effects in human but the gene expression profiles leading to development of differnet diseases and disorders are not fully understood. The knowledge of global gene expression will help us to devlop early disease or dis...
ORGANISM(S): Homo sapiens 
2013-05-31 | E-GEOD-28805 | biostudies-arrayexpress
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