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ProteomicsDiscovery from in-depth molecular analyses of giant viruses: Haptophyte-infecting viruses change the genome condensing proteins of dinoflagellates
Giant viruses are extraordinary members of the virosphere due to their structural complexity and high diversity in gene content. Haptophytes are ecologically important primary producers in the ocean, and all known viruses that infect haptophytes are giant viruses. Our in-depth electron microscopic, ...
ORGANISM(S): Prymnesium kappa virus 
2025-02-21 | PXD060762 | Pride
Haptolina ericina virus Giant viruses Haptophytes Prymnesium kappa virus 
GenomicsGiant panda picorna-like virus
Giant panda picorna-like virus Genome sequencing
PRJNA612982 | ENA
ProteomicsLatent infection of an active giant endogenous virus in a unicellular green alga
Latency is a common strategy in a wide range of viral lineages, but its prevalence in giant viruses remains unknown. Here we describe the activity and viral production from a 617 kbp integrated giant viral element in the model green alga Chlamydomonas reinhardtii. We resolve the integrated viral reg...
ORGANISM(S): Nucleocytoviricota 
2025-06-16 | PXD060118 | Pride
Chlamydomonas reinhardtii Giant endogenous viral elements (geve) 
ProteomicsIntegrative structural Interactomics reveals protein organization and structure in a giant virus
Giant viruses are large DNA viruses that infect unicellular and multicellular eukaryotes and form exceptionally large extracellular particles. (Meta)genomics and (meta)transcriptomics have provided insight into their diverse coding repertoire, but many of the proteins remain to be characterized as t...
ORGANISM(S): Melbournevirus Acanthamoeba castellanii str. Neff 
2026-05-20 | PXD064933 | Pride
Cross-linking mass spectrometry Bottom-up proteomics Giant virus 
TranscriptomicsRoles and Programming of Arabidopsis ARGONAUTE Proteins During Turnip Mosaic Virus Infection
AGO protein immunoprecipitation was combined with high-throughput sequencing of associated small RNAs. AGO2, AGO10, and to a lesser extent AGO1 were shown to associate with siRNAs derived from silencing suppressor (HC-Pro)-deficient TuMV-AS9, but not with siRNAs derived from wild-type TuMV. Co-immun...
ORGANISM(S): Arabidopsis thaliana 
2015-04-06 | E-GEOD-64911 | biostudies-arrayexpress
ProteomicsProteomic characterization of Zamilon vitis virions produced in various contexts
Acanthamoeba-infecting Mimiviridae belong to three clades: Mimiviruses (A), Moumouviruses (B) and Megaviruses (C). The uniquely complex mobilome of these giant viruses includes virophages and linear 7 kb-DNA molecules called “transpovirons”. We recently isolated a new virophage (Zamilon vitis) and t...
ORGANISM(S): unclassified virophages Mimiviridae 
2020-04-14 | PXD009037 | Pride
Virophage Transpoviron Virion proteomics Mimiviridae Giant virus 
TranscriptomicsTrophoblast giant cell underrepresentation (CGH)
We characterized regions of underrepresentation that are specific to mouse polyploid trophoblast giant cells. We performed array Comparative Genomics Hybridization (aCGH) to examine copy number variation (CNV) in mouse polyploid trophoblast giant cells (TGCs). We performed the following experiments...
ORGANISM(S): Mus musculus 
2014-05-29 | E-GEOD-50543 | biostudies-arrayexpress
TranscriptomicsGene expression based analysis of CroV infection of Cafeteria roenbergensis
In this study, total RNA was extracted from cultures of Cafeteria infected with the Cafeteria roenbergensis virus BV-PW1 (CroV) and hybridised to a CroV microarray in order to determine the temporal expression profile during infection. A straightforward measure of whether each spot was on or off was...
ORGANISM(S): Cafeteria roenbergensis virus BV-PW1 
2010-07-18 | E-GEOD-19051 | biostudies-arrayexpress
ProteomicsMS-based proteomic characterization of Megavirus chilensis virions prepared from cells coinfected or not with Zamilon vitis
Nested parasitic chains are common schemes in nature, not limited to cellular organisms. Some giant viruses infecting protists are hyperparasitized by smaller viruses named virophages. Both can carry episomal plasmid-like DNA molecules known as transpovirons in their particles. They all share common...
ORGANISM(S): Acanthamoeba castellanii Zamilon virus Megavirus chiliensis 
2024-09-03 | PXD052049 | Pride
Mobilome Giant virus Virion Nanolc-ms/ms 
GenomicsCultivation and Genomics of a Giant Virus infecting the Cryptophyte Rhodomonas
Cultivation and Genomics of a Giant Virus infecting the Cryptophyte Rhodomonas
PRJEB65831 | ENA
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