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TranscriptomicsGene expression profiling of enforced HOXA1 expression in melanoma cell line
We recently reported an oncogenomics-guided screening approach designed to identify genetic drivers of early stage melanoma metastasis, and in this study we functionally validate the top-scoring candidate, homeobox transcription factor A1 (HOXA1), by demonstrating HOXA1‘s robust effects on melanom...
ORGANISM(S): Homo sapiens 
2013-01-08 | E-GEOD-37136 | biostudies-arrayexpress
GenomicsLigand-dependent dynamics of retinoic acid receptor binding during early neurogenesis
Among its many roles in development, retinoic acid determines the anterior-posterior identity of differentiating motor neurons by activating Retinoic Acid Receptor (RAR)-mediated transcription. RAR is thought to bind the genome constitutively, and only induce transcription in the presence of the ret...
ORGANISM(S): Mus musculus 
2010-12-10 | E-GEOD-19409 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of enforced HOXA1 expression in melanoma cell line (SkMel30)
We recently reported an oncogenomics-guided screening approach designed to identify genetic drivers of early stage melanoma metastasis, and in this study we functionally validate the top-scoring candidate, homeobox transcription factor A1 (HOXA1), by demonstrating HOXA1 robust effects on melanoma ce...
ORGANISM(S): Homo sapiens 
2013-01-01 | E-GEOD-40422 | biostudies-arrayexpress
UnknownHOXA1 drives melanoma tumor growth and metastasis and elicits an invasion gene expression signature that prognosticates clinical outcome.
Not available
S-EPMC3982326 | biostudies-literature
UnknownGene expression profiling of enforced HOXA1 expression in melanoma cell line
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-37136 | biostudies-other
UnknownDevelopment and validity evidence for the resident-led large group teaching assessment instrument in the United States: a methodological study.
Not available
S-EPMC10948941 | biostudies-literature
UnknownT cell memory response to MPXV infection exhibits greater effector function and migratory potential compared to MVA-BN vaccination.
Not available
S-EPMC12065855 | biostudies-literature
TranscriptomicsExpression time series during the differentiation of ventral motor neurons from embryonic stem cells
The aim of this study is to profile gene expression dynamics during the in vitro differentiation of embryonic stem cells into ventral motor neurons. Expression levels were profiled using Affymetrix microarrays at six timepoints during in vitro differentiation: ES cells (Day 0), embryoid bodies (Day ...
ORGANISM(S): Mus musculus 
2010-12-10 | E-GEOD-19372 | biostudies-arrayexpress
TranscriptomicsRapid clearance of PcG histone modifications from Hox genes anticipates motor neuron differentiation: ChIP-chip
[original Title] Rapid and synchronous clearance of PcG histone modifications from Hox genes anticipates motor neuron differentiation. Hox genes are expressed in patterns that are spatially and temporally collinear with their chromosomal organization. This feature is an evolutionarily conserved hall...
ORGANISM(S): Mus musculus 
2013-07-04 | E-GEOD-19447 | biostudies-arrayexpress
UnknownGWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.
Not available
S-EPMC10208981 | biostudies-literature
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