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ProteomicsProteomic Discovery and Validation of Diagnostic Plasma Biomarkers for Pulmonary Tuberculosis
Despite more than a century fighting against tuberculosis, the World Health Organisation has estimated that around 1.7 million people died of tuberculosis in 2016 and over a quarter of the world’s population is infected. One of the critical hurdles for stopping tuberculosis transmission is early and...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD020212 | Pride
Plasma Tuberculosis Shotgun Hyper-fractionation Wgcna Biomarkers Itraq 
TranscriptomicsTranscription profiling of Bos taurus mucosal derived ab and gd T cells during Salmonella enterica serovar typhimurium enterocolitis
gd T cells have an important yet incompletely defined role in inflammation associated with a variety of infectious and autoimmune conditions. To better understand the precise roles of gd T cells relative to ab T cells in a specific infection, we utilized Salmonella Enterica Serovar Typhimurium (S. ...
ORGANISM(S): Bos taurus 
2008-11-08 | E-GEOD-3439 | biostudies-arrayexpress
TranscriptomicsRole of Ror2 in primordial germ cell migration
Primordial germ cells (PGCs), the embryonic precursors of eggs and sperm, are a unique model for identifying and studying regulatory mechanisms in singly migrating cells. From their time of specification to eventual colonization of the gonad, mouse PGCs traverse through and interact with many differ...
ORGANISM(S): Mus musculus 
2014-08-08 | E-GEOD-60179 | biostudies-arrayexpress
TranscriptomicsFetal transcripts in maternal blood
The discovery of fetal mRNA transcripts in maternal circulation holds great promise for noninvasive prenatal diagnosis. To identify potential fetal biomarkers, we studied whole blood and plasma transcripts common to term pregnant women and their newborns but reduced or absent in the postpartum mothe...
ORGANISM(S): Homo sapiens 
2014-01-08 | E-GEOD-53669 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Corynebacterium glutamicum shows a differential response to moderate or severe heat shock of the HrcA- and HspR-dependent systems
Genome-wide transcription profiles analysis of the heat-shocked wild-type strain under moderate (40¡C) and severe heat stress (50¡C) revealed that a large number of genes are differentially expressed after heat shock. 358 genes were up-regulated and 420 were down-regulated in response to moderate he...
ORGANISM(S): Corynebacterium glutamicum 
2008-12-10 | E-MTAB-66 | biostudies-arrayexpress
TranscriptomicsTranscriptomic profiling of immune and stromal cells from the non small cell lung cancer (NSCLC) environment
T lymphocytes can efficiently counteract the growth of tumors within the tumor microenvironment. Specialized immune-interacting fibroblasts, termed fibroblastic reticular cells (FRC) are responsible for the formation of specialized niches promoting immune cell activation in secondary lymphoid organs...
ORGANISM(S): Homo sapiens 
2024-11-19 | E-MTAB-13710 | biostudies-arrayexpress
TranscriptomicsA comparison of mono-culture and co-culture model containing fibroblasts
Organotypic three dimensional cultures of epithelial cells are grown at the air–liquid interface (ALI) and resemble the in vivo counterparts. Although the complexity of in vivo cellular responses could be better manifested in co-culture models in which additional cell-types such as fibroblasts were ...
ORGANISM(S): Homo sapiens 
2015-06-12 | E-MTAB-3462 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human tetraploid and polyploid (8N and 16N) megakaryocytes to identify genes which are up and down regulated during megakaryocyte differentiation/polyploidization
The aim of the experiment was to characterize by a pan-genomic approach genes which are continuously up and down regulated during polyploidization during megakaryocyte differentiation.
ORGANISM(S): Homo sapiens 
2007-04-16 | E-TABM-133 | biostudies-arrayexpress
UnknownTKI-Mediated Inhibition of NLRP1 Inflammasome Restores Erythropoiesis in DBA Syndrome
Not available
S-SCDT-10_1038-S44321-025-00368-3 | biostudies-other
Genomicsena-DATASET-ICR-PTGT-28-07-2015-16:51:33:172-264 - samples
Anaplastic oligodendrogliomas (AOs) are rare primary brain tumors which are generally incurable, with heterogeneous prognosis and few treatment targets identified. Most oligodendrogliomas have chromosome 1p/19q co-deletion and IDH mutation. We analyzed 51 AOs by whole-exome sequencing, identifying p...
EGAD00001001452 | EGA
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