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The human cell nucleus is comprised of proteins, chromatin and RNA, yet how they interact to form supramolecular structures and drive key biological processes remains unknown. Conflicting models have proposed either a fluid-like or solid-like nature for the intranuclear microenvironment. To reconcil...
ORGANISM(S): Homo sapiens (Human) 
2024-06-18 | PXD053208 | Pride
Genomic comparison of more and less invasive strains of Neisseria meningitidis
ORGANISM(S): Neisseria meningitidis 
Analysis of 30nm Chromatin Structure in Female Human SATO3 Lymphoblastoid Cells Single Input and Replicate Open Chromatin Samples Prepared from Cell Line
ORGANISM(S): Homo sapiens 
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
This study was designed to investigate DNA supercoiling across the human genome and to understand how supercoiling domains impact on higher levels of genome organisation. DNA supercoiling is an inherent consequence of twisting DNA and is critical for regulating gene expression and DNA replication. H...
ORGANISM(S): Homo sapiens 
This study was designed to investigate DNA supercoiling across the human genome and to understand how supercoiling domains impact on higher levels of genome organisation. DNA supercoiling is an inherent consequence of twisting DNA and is critical for regulating gene expression and DNA replication. H...
ORGANISM(S): Homo sapiens 
This study was designed to investigate DNA supercoiling across the human genome and to understand how supercoiling domains impact on higher levels of genome organisation. DNA supercoiling is an inherent consequence of twisting DNA and is critical for regulating gene expression and DNA replication. H...
ORGANISM(S): Homo sapiens 
Here we characterized and compared differential gene expression from diabetic and normoglycemic NOD mice and from aged and young-adults Balb/c mice. Total RNA from NOD diabetic (3 weeks with glicemia over 500mg/dl) and normoglycemic NOD mice from the same age was used. To compare the effects of agin...
ORGANISM(S): Mus musculus 
WTCCC1 project Autoimmune Thyroid Disease (ATD) samples
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