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MetabolomicsSAR11 Cells Rely on Enzyme Multifunctionality to Transport and Metabolize a Range of Polyamine Compounds
In the ocean surface layer and cell culture, the polyamine transport protein PotD of SAR11 bacteria is often one of the most abundant proteins detected. Polyamines are organic cations at seawater pH produced by all living organisms and are thought to be an important component of dissolved organic ma...
2021-09-09 | MTBLS3146 | MetaboLights
ProteomicsSpatial lipidomic profiling of mouse joint tissue demonstrates the essential role of PHOSPHO1 in growth plate homeostasis
Lipids play a crucial role in signalling and metabolism, regulating the development and maintenance of the skeleton. Membrane lipids have been hypothesised to act as intermediates upstream of orphan phosphatase 1 (PHOSPHO1), a major contributor to phosphate generation required for bone mineralisatio...
ORGANISM(S): Mus musculus (Mouse) 
2023-04-19 | PXD038909 | Pride
Mouse Maldi-ims Phospho1 Matrix mineralisation Disorders of calcium or phosphate metabolism Lipids Knee joint Growth plate Bone modelling and remodelling 
ProteomicsMass spectrometry analysis of degenerated human intervertebral disc tissues
Mass spectrometry analysis of degenerated human intervertebral disc tissues obtained during elective surgery to treat low back pain
ORGANISM(S): Homo sapiens (Human) 
2025-02-14 | PXD056620 | Pride
Human Degeneration Mass spectometry Intervertebral disc Dda 
UnknownPembrolizumab for Platinum- and Cetuximab-Refractory Head and Neck Cancer: Results From a Single-Arm, Phase II Study.
Not available
S-EPMC5946724 | biostudies-literature
ProteomicsSWATH DIA MS data of human plasma from donors with intervertebral disc degeneration
SWATH DIA mass spectometry was peformed on plasma samples from donors with mild or severe intervetebral disc degeneration to identify biomarkers associated with degeneration progression.
ORGANISM(S): Homo sapiens (Human) 
2025-02-14 | PXD055158 | Pride
Human Plasma Ivd Intervetebral Disc degeneration 
UnknownAn expanded mammal mitogenome dataset from Southeast Asia.
Not available
S-EPMC5737531 | biostudies-literature
UnknownTherapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.
Not available
S-EPMC4962737 | biostudies-literature
TranscriptomicsDistinct classes of genes behave as either drivers or dependents of replication timing switches (Replication-Timing).
Duplication of the genome in mammalian cells occurs in a defined temporal order referred as its replication-timing program (RT). RT is regulated in units of 400-800 Kb referred as replication domains (RDs) and changes dynamically during development. Changes in RT are generally coordinated with trans...
ORGANISM(S): Homo sapiens 
2015-05-28 | E-GEOD-63428 | biostudies-arrayexpress
ProteomicsVestibular schwannoma is comprised of neural crest and immune subgroups
Vestibular schwannomas (VS) are tumors arising from cranial nerve Schwann cells that cause significant morbidity and are treated with surgery and irradiation. We describe a DNA methylation-based classification of VS into neural crest and immune enriched subgroups and validate our findings using bulk...
ORGANISM(S): Homo Sapiens 
PXD014883 | panorama
GenomicsATD
WTCCC1 project Autoimmune Thyroid Disease (ATD) samples
EGAD00000000011 | EGA
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