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ORGANISM(S): Homo sapiens 
The angio-suppressive effect of 20(R)-ginsenoside Rg3 (Rg3-R) has been previously demonstrated, and microRNAs (miRNAs) are a vital group of small non-coding RNAs that function as post-transcriptional modulator of gene expression. Thus, using human umbilical vein endothelial cells (HUVEC) as model, w...
ORGANISM(S): Homo sapiens 
The breast cancer incidence has been increasing in China, with the earlier age of onset compared with Western countries. Traditional Chinese medicine has been provided as one of the major source of anti-cancer drugs. Ginseng is one of the most common traditional medicines in China. Ginsenosides, the...
ORGANISM(S): Homo sapiens (Human) 
2018-01-08 | PXD003092 | Pride
Ginsenoside Rg3 attenuates allergic asthma in mice via transcriptomics
Ginsenoside Rg3 Mitigates Neurodegeneration by Enhancing Lysosomal Function through the mTOR–TFEB Axis
ObjectivesThis study aims to investigate the molecular mechanism by which ginsenoside Rg3 attenuates allergic asthma. Methods: This study established an ovalbumin (OVA)-induced mouse model of allergic asthma to explore the anti-allergic effects and potential molecular mechanisms of ginsenoside Rg3. ...
ORGANISM(S): Mus musculus 
2026-04-08 | GSE325101 | GEO
RNA sequencing was performed to investigate the transcriptomic responses of day 5 adult Caenorhabditis elegans to ginsenoside Rg3 treatment. Age-synchronized N2 worms were treated with 5 μg/mL ginsenoside Rg3 or vehicle control, and whole-worm RNA was subjected to high-throughput sequencing. Differe...
ORGANISM(S): Caenorhabditis elegans 
2026-09-30 | GSE339194 | GEO
This study aims to explore the potential mechanism of Ginsenoside Rg3 against gastric cancer,we first found that the anti-GC cell proliferation by Rg3 in part is via inhibiting the formation of E2F-DP heterodimers, and suppressing the p53-p21-cyclin/CDKs-RB signaling pathway. These find-ings highlig...
ORGANISM(S): Homo sapiens 
2025-09-01 | GSE275773 | GEO
lncRNA sequencing of human ovarian cancer cell SKOV3 after exposure to ginsenoside 20(S)-Rg3
The angio-suppressive effect of 20(R)-ginsenoside Rg3 (Rg3-R) has been previously demonstrated, and microRNAs (miRNAs) are a vital group of small non-coding RNAs that function as post-transcriptional modulator of gene expression. Thus, using human umbilical vein endothelial cells (HUVEC) as model, w...
ORGANISM(S): Mus musculus Homo sapiens Caenorhabditis elegans Drosophila melanogaster Rattus norvegicus Danio rerio 
2011-09-10 | GSE31959 | GEO
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