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UnknownRole of Akt signaling in resistance to DNA-targeted therapy.
Not available
S-EPMC5056327 | biostudies-literature
UnknownFOLFIRINOX and translational studies: Towards personalized therapy in pancreatic cancer.
Not available
S-EPMC4988311 | biostudies-literature
ProteomicsHuman Pancreatic Ductal Adenocarcinoma (PDAC), LC-MS/MS
The aim of the study was to characterize a common molecular mechanism for paclitaxel resistance in Patu-T and Suit-2.028 PDAC cell lines. Despite the ATP-binding cassette (ABC) trasnsporters were already shown to be involved in various chemo-resistant forms of cancers but not in PDAC, the most likel...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD040930 | Pride
Human Pdac cell models Pancreas Lc-ms/ms 
TranscriptomicsHuman lung adenocarcinoma NCI-H1975 cells: parental vs cell lines resistant to the EGFR-TK inhibitor CNX-2006
Genome variation profiling of lung adenocarcinoma cells comparing untreated NCI-H1975 cells with CNX-2006-resistant untreated cells. Goal was to determine the potential mechanism of resistance to mutant EGFR-TKIs and rationally design novel strategies for the treatment of EGFR-mutant lung cancer pat...
ORGANISM(S): Homo sapiens 
2015-07-01 | E-GEOD-53234 | biostudies-arrayexpress
UnknownDarifenacin: a promising chitinase 3-like 1 inhibitor to tackle drug resistance in pancreatic ductal adenocarcinoma.
Not available
S-EPMC11438711 | biostudies-literature
ProteomicsCombined expression of plasma CA19-9 and thrombospondin-2 for accurate diagnosis of pancreatic cancer and distal cholangiocarcinoma– A proteome approach
Minimally- invasive diagnostic biomarkers for patients with pancreatic ductal adenocarcinoma (PDAC) and distal cholangiocarcinoma (CCA) are warranted to enhance early and accurate diagnosis. This study identified tumor tissue secreted proteins, the “secretome”, which was analysed for differential ca...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD012480 | Pride
Thbs2 Thrombospondin-2 Early detection Cholangiocarcinoma Label-free Pdac Pancreatic cancer 
UnknownAKT1 and SELP polymorphisms predict the risk of developing cachexia in pancreatic cancer patients.
Not available
S-EPMC4169595 | biostudies-literature
UnknownRole of c-MET Inhibitors in Overcoming Drug Resistance in Spheroid Models of Primary Human Pancreatic Cancer and Stellate Cells.
Not available
S-EPMC6562408 | biostudies-literature
UnknownNovel FAK inhibitors suppress tumor growth and reverse EGFR-TKI resistance in non-small cell lung cancer.
Not available
S-EPMC12635985 | biostudies-literature
UnknownUnraveling resistance mechanisms to the novel nucleoside analog RX-3117 in lung cancer: insights into DNA repair, cell cycle dysregulation and targeting PKMYT1 for improved therapy.
Not available
S-EPMC12288264 | biostudies-literature
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