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ProteomicsCombined expression of plasma CA19-9 and thrombospondin-2 for accurate diagnosis of pancreatic cancer and distal cholangiocarcinoma– A proteome approach
Minimally- invasive diagnostic biomarkers for patients with pancreatic ductal adenocarcinoma (PDAC) and distal cholangiocarcinoma (CCA) are warranted to enhance early and accurate diagnosis. This study identified tumor tissue secreted proteins, the “secretome”, which was analysed for differential ca...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD012480 | Pride
Thbs2 Thrombospondin-2 Early detection Cholangiocarcinoma Label-free Pdac Pancreatic cancer 
UnknownBiophysical characterization of the signature domains of thrombospondin-4 and thrombospondin-2.
Not available
S-EPMC2219889 | biostudies-literature
GenomicsFibroblast-Derived Thrombospondin 2 Shapes the Immune-Exclusionary Environment at Invasive Fronts in Colorectal Cancer [RNA-seq_Human_CRC]
Fibroblast-Derived Thrombospondin 2 Shapes the Immune-Exclusionary Environment at Invasive Fronts in Colorectal Cancer [RNA-seq_Human_CRC]
PRJNA1204097 | ENA
GenomicsFibroblast Derived Thrombospondin-2 Shapes the Immune-Exclusionary Environment at Invasive Fronts in Colorectal Cancer [RNA-seq_Mouse_CAF]
Fibroblast Derived Thrombospondin-2 Shapes the Immune-Exclusionary Environment at Invasive Fronts in Colorectal Cancer [RNA-seq_Mouse_CAF]
PRJNA1204099 | ENA
GenomicsFibroblast-Derived Thrombospondin 2 Shapes the Immune-Exclusionary Environment at Invasive Fronts in Colorectal Cancer [scRNA-seq]
Fibroblast-Derived Thrombospondin 2 Shapes the Immune-Exclusionary Environment at Invasive Fronts in Colorectal Cancer [scRNA-seq]
PRJNA1204095 | ENA
GenomicsFibroblast-Derived Thrombospondin 2 Shapes the Immune-Exclusionary Environment at Invasive Fronts in Colorectal Cancer [RNA-seq_Mouse_Tumor]
Fibroblast-Derived Thrombospondin 2 Shapes the Immune-Exclusionary Environment at Invasive Fronts in Colorectal Cancer [RNA-seq_Mouse_Tumor]
PRJNA1204094 | ENA
UnknownContribution of Thrombospondin-1 and -2 to Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome.
Not available
S-EPMC8087994 | biostudies-literature
ProteomicsCompound Deletion of Thrombospondin-1 and -2 Results in a Skeletal Phenotype not Predicted by the Single Gene Knockouts
The trimeric thrombospondin homologs, TSP1 and TSP2, are both components of bone tissue and contribute in redundant and distinct ways to skeletal physiology. The functional effects of combined TSP1 and TSP2 deficiency remain to be elucidated. Here, we examined the spectrum of detergent soluble prot...
ORGANISM(S): Mus musculus (Mouse) 
2021-08-26 | PXD020832 | Pride
Thrombospondins Bone Osteoblasts Osteoclasts 
UnknownMacroglia-derived thrombospondin 2 regulates alterations of presynaptic proteins of retinal neurons following elevated hydrostatic pressure.
Not available
S-EPMC5617560 | biostudies-literature
TranscriptomicsFibroblast-Derived Thrombospondin 2 Shapes the Immune-Exclusionary Environment at Invasive Fronts in Colorectal Cancer [RNA-seq_Mouse_Tumor]
Fibrotic colorectal cancers (CRC) are characterized by immune exclusion driven by activated stroma, particularly by cancer-associated fibroblasts (CAFs). We identified that the matricellular protein thrombospondin-2 (THBS2) is highly expressed in the stroma of fibrotic CRCs. We performed orthotopic ...
ORGANISM(S): Mus musculus 
2025-10-28 | GSE285501 | GEO
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