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TranscriptomicsDifferential Effects Of The Anti-Obesity Drug Tirzepatide On Adipose Tissues: Brown Fat As A Key Target
Tirzepatide is an anti-obesity drug based on dual agonism of the incretin receptors GLP-1R and GIPR. Its anti-obesity effect is largely based on its action of reducing food intake. However, there are suggestive indications that tirzeparide may exert effects on adipose tissues beyond those resulting ...
ORGANISM(S): Mus musculus 
2026-02-16 | E-MTAB-15994 | biostudies-arrayexpress
ProteomicsTargeted and partial in vivo reprogramming of hippocampal neurons restores memory loss and neural synchrony in a mouse model of Alzheimer’s disease
Alzheimer’s disease (AD) is the most common neurodegenerative disorder with a huge impact on society due to its prevalence. Major risk factor to develop AD is aging. Indeed, most of the physiopathological events described in AD are also hallmarks of accelerated aging. To counteract accelerated aging...
ORGANISM(S): Mus Musculus (mouse) 
2026-07-22 | PXD066415 | JPOST Repository
TranscriptomicsExposure to aerosol of an e-vapor device with MESH™ technology had a lower biological impact than exposure to cigarette smoke on human bronchial and alveolar culture models: an in vitro systems toxicology assessment.
The harmful effects of cigarette smoke exposure on the respiratory tract are widely known. Exposure to aerosol from electronic vapor (e-vapor) products has been suggested to result in less risk of harm to smokers than CS exposure. Many studies have assessed the potential toxicity of the aerosol from...
ORGANISM(S): Homo sapiens 
2021-01-31 | E-MTAB-10071 | biostudies-arrayexpress
UnknownChaperone-mediated autophagy controls brown adipose tissue thermogenic activity.
Not available
S-EPMC12571069 | biostudies-literature
UnknownAdult neural stem cells and neurogenesis are resilient to intermittent fasting
Not available
S-SCDT-10_15252-EMBR_202357268 | biostudies-other
UnknownImpact of Toxicity on Survival for Older Adult Patients after CD34+ Selected Allogeneic Hematopoietic Stem Cell Transplantation.
Not available
S-EPMC6731766 | biostudies-literature
UnknownThe Impact of Toxicities on First-Year Outcomes after Ex Vivo CD34+-Selected Allogeneic Hematopoietic Cell Transplantation in Adults with Hematologic Malignancies.
Not available
S-EPMC7376603 | biostudies-literature
UnknownStroke Genetics Network (SiGN) study: design and rationale for a genome-wide association study of ischemic stroke subtypes.
Not available
S-EPMC4056331 | biostudies-literature
UnknownPathogenic ischemic stroke phenotypes in the NINDS-stroke genetics network.
Not available
S-EPMC4286169 | biostudies-literature
UnknownDeploying unsupervised clustering analysis to derive clinical phenotypes and risk factors associated with mortality risk in 2022 critically ill patients with COVID-19 in Spain.
Not available
S-EPMC7883885 | biostudies-literature
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